宁光院士发布国人代谢指数 可评估心血管发病概率

2017-11-23 渝小苏 医学界内分泌频道

11月23日,中华医学会糖尿病学分会第二十一次全国学术会议(CDS2017)在重庆盛大召开。

11月23日,中华医学会糖尿病学分会第二十一次全国学术会议(CDS2017)在重庆盛大召开。

在开幕式现场,中国工程院院士、上海交通大学医学院附属瑞金医院副院长宁光教授以《中国糖尿病防治及研究实践及策略性思考》为题,介绍了我国糖尿病防治领域的重要研究进展与思路,同时发布了2项与临床医生和普通民众最直接相关的最新研究成果——中国人“代谢指数”和“饮食地图”。

宁光院士现场演讲

只需6个参数,预测3年心血管病风险

生活方式改变、老龄化和肥胖是中国糖尿病流行的3大主因,同时中国成年人心血管健康达标率仅13.5%。如何预防糖尿病和心血管风险尤其增加普通民众的疾病知晓率迫在眉睫。

在演讲中,宁院士代表国家代谢性疾病管理中心(MMC)发布了最新研究成果——“瑞宁预糖”中国代谢疾病健康指数(以下简称“代谢指数”),用以评估中国人3年内发生心血管疾病的概率。

据现场介绍,该代谢指数的建立基于REACTION研究(中国人群糖代谢与恶性肿瘤发生风险多中心前瞻性研究)内的25万中国人队列参数及3年随访数据,综合深度学习技术,并已在大型人群中进行验证,具有良好的准确性和可信性。

普通中国成年人只需要输入2项基本信息(性别、年龄)以及4项代谢综合征组分(血压、血糖、血脂、体重),即可计算代谢性疾病指数(满分100分),用以评估3年内发生心血管病的概率。


代谢指数设计思路、分值风险对照表、初步人群调查结果

分数值越低,心血管病风险越高:0-9分的人群3年内发生心血管疾病概率高至18.75%,而90-100分的人群风险则降低至0.12%。

“瑞宁预糖”前期数据显示,在中国45岁以上人群中,代谢指数位于60分左右的人数最多,平均3年发生心血管病的风险约为1.54%左右,女性得分高于男性。研究组根据前期研究数据,绘制了具有省份特征的“中国代谢指数地图”。


中国代谢指数地图

从地图可以看出,辽宁、北京、天津、河北、江苏、上海、重庆、广东等地的代谢指数偏低,总体人群心血管风险高于其他省份。

除“瑞宁预糖”外,上周MMC还发布了同样基于REACTION研究结果设计的“瑞宁知糖”中国糖尿病风险评估系统,用最简便的参数和科学的方法早发现早干预普通人群糖尿病发病风险。

普通成年人只需输入个人基本信息(如性别、年龄、身高、体重、教育状况、饮酒吸烟等,无需输入血糖水平)即可算出近3年内糖尿病患病风险(≥7%为危险,≥12%为高危)。

在开幕式上,宁光院士发布了“瑞宁知糖”截止目前的人群调查结果:16.6%的受调查者具有2型糖尿病高危风险,29.5%受试者处于超重状态,27.9%患有脂肪肝,18.6%患有高血压,16%有吸烟史,高达40%有饮酒史,可见2型糖尿病风险防控刻不容缓。


“瑞宁知糖”人群调查结果

300亿大数据告诉你,究竟吃什么预防糖尿病?

除“代谢指数”之外,宁光院士还在CDS开幕式演讲中揭示了一项非常“有趣”的最新研究——“国人饮食行为地图”。

宁院士团队2016年根据300亿以上搜索数据、涵盖2.1亿人口的网络标签,选取饮食烹饪倾向的数据,对中国人的饮食行为进行分析,研究发现:

喜煎炸人群多分布在东北和华北,此高热量饮食习惯与低气温分布接近;

喜烧烤人群多分布在东北和京津冀,海南受移民影响烧烤喜爱程度也较高;

喜煎炸和烧烤人群地图

喜辣地区多分布在西南及西北地区;

喜涮人群多分布在四川附近和北京,为“火锅文化”主导地区;

喜辣和喜涮人群地图

生鲜地区分布不明显;

喜生鲜人群地图

从年龄分布来看,烧烤、辣等“重口味”受年轻人喜欢,25-34岁人群最多,喜爱程度并随年龄的增长而减少,而生鲜的比例则不变。

那么,这些饮食倾向与2型糖尿病发病率是否有关联呢?答案是肯定的。研究组通过大数据筛选分析的初步结果显示:辛辣饮食能够减少糖尿病发病,而油炸食品增加糖尿病发病。

一句话就是说,“多吃辣,少油炸”或能成为预防糖尿病的重要饮食“处方“!


国人饮食行为年龄分布与糖尿病关系

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    2018-08-25 zhmscau
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    2017-11-25 孙文杰

    果断收藏.值得推荐

    0

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    2017-11-24 明天会更好!

    学习了.谢谢分享.

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2006253, encodeId=1931200625301, content=<a href='/topic/show?id=19764565e19' target=_blank style='color:#2F92EE;'>#宁光院士#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45657, encryptionId=19764565e19, topicName=宁光院士)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKCRibWHQArPHdSkqP90U1HwwqlGeU7BUgzY240D3v2ibBDJ09ybkGkwOjxz7qRmngZaGlK1taX6hfA/132, createdBy=2e772500094, createdName=小华子, createdTime=Fri Mar 02 00:38:00 CST 2018, time=2018-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1649162, encodeId=909e1649162f0, content=<a href='/topic/show?id=2468456550a' target=_blank style='color:#2F92EE;'>#宁光#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45655, encryptionId=2468456550a, topicName=宁光)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=fb4f23763610, createdName=zhmscau, createdTime=Sat Aug 25 01:38:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264202, encodeId=1b8826420211, content=果断收藏.值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/y1ZJaAFo7AFqm7Hn2QNVTjOpBV9mRicUEjyBqRMnLADF1oQXJGeIVCpiaY1hJVMd1C40EhFCw4LL8sCKTx8Yuvsw/132, createdBy=af0b1960284, createdName=孙文杰, createdTime=Sat Nov 25 14:25:10 CST 2017, time=2017-11-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263892, encodeId=8c5726389241, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Fri Nov 24 08:57:41 CST 2017, time=2017-11-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=263891, encodeId=e73f263891d8, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Fri Nov 24 08:57:36 CST 2017, time=2017-11-24, status=1, ipAttribution=)]
    2017-11-24 明天会更好!

    学习了.谢谢分享.

    0