BMC Oral Health:光动力疗法(PDT)对粪肠球菌生物膜的抑菌效果

2015-01-16 sunshine 译 MedSci原创

背景:为了确定在人类实验性根管的原发性感染以及继发性感染根管再治疗中光动力疗法对粪肠球菌生物膜的抑菌效果 方法:选择160颗离体单根牙,单管型,使用ProTaper对其进行根管预备。其中,70个样本未经根管充填和热压处理。另外,选择70个根管用Thermafil热塑牙胶和AH Plus糊剂充填,24小时之后用ProTaper D锉去除根充物并用等离子灭菌。用从临床分离的粪肠球菌感染这些样本7

背景:


为了确定在人类实验性根管的原发性感染以及继发性感染根管再治疗中光动力疗法对粪肠球菌生物膜的抑菌效果

方法:

选择160颗离体单根牙,单管型,使用ProTaper对其进行根管预备。其中,70个样本未经根管充填和热压处理。另外,选择70个根管用Thermafil热塑牙胶和AH Plus糊剂充填,24小时之后用ProTaper D锉去除根充物并用等离子灭菌。用从临床分离的粪肠球菌感染这些样本72小时。然后用无菌纸尖采集样本以确定根管内存在粪肠球菌。根据牙齿所接受的治疗将其随机分为实验组和对照组,每组各20颗牙齿。PDT组,用PDT处理牙齿,PDT包括光敏剂甲苯胺蓝和波长为635nm的光源。NaOCl(次氯酸钠)组,用3%的次氯酸钠10ml冲洗根管。NaOCl-PDT组,先用3%的次氯酸钠10ml冲洗根管,然后用PDT处理。经过这些处理后,用无菌纸尖采集样本。另外,收集位于根管壁上残留的根管充填材料。通过计数菌落形成单位计算样品的存活分数。运用单因素方差分析数据,评价不同治疗方法的效果。

结果:

所有分组均显示,根管内抗菌治疗能显著减少根管内的细菌量。次氯酸钠根管内冲洗对于清除粪肠球菌最为有效。与次氯酸钠根管内冲洗以及次氯酸钠根管内冲洗联合PDT相比,单独使用PDT效果较差一些。从经次氯酸钠冲洗过的根管充填材料中采集的CFU水平是PDT以及次氯酸钠冲洗联合PDT的10倍。


如图所示:扫描电镜放大5000倍观察定植在根管内牙本质以及根管充填材料(软化热牙胶和AH Plus糊剂)中的粪肠球菌。用3%次氯酸钠冲洗根管或者使用PDT能显著减少位于牙本质内以及根管充填材料表面的粪肠球菌。经过处理后,仅能发现少数形态正常的细菌细胞位于热牙胶和AH Plus糊剂中。剩余的细胞在处理过的牙本质中表现出异常的形状。

结论:

在实验性根管的原发性感染以及继发性感染根管再治疗中,光动力疗法能减少根管内的粪肠球菌。虽然相对于PDT,次氯酸钠根管内冲洗对于清除粪肠球菌更为有效。但是对于清除定植于根管内残余的充填材料中的粪肠球菌来说,PDT比3%次氯酸钠根管内冲洗更为有效。在根管消毒过程中,PDT不是不可或缺的,但却是一个有效的辅助手段,尤其是对于根管再感染的治疗。基于传统的治疗方法,在使用PDT之前联合使用次氯酸钠进行根管内冲洗以破坏菌斑生物膜仍是必要的。

原始出处:

Tennert C1, Feldmann K, Haamann E, Al-Ahmad A, Follo M, Wrbas KT, Hellwig E, Altenburger MJ.Effect of photodynamic therapy (PDT) on Enterococcus faecalis biofilm in experimental primary and secondary endodontic infections.BMC Oral Health. 2014 Nov 4;14:132. doi: 10.1186/1472-6831-14-132.


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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

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    2015-01-29 zlawrance
  3. 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createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
    2015-09-10 小几洁
  4. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
    2015-09-03 江川靖瑶
  5. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
    2015-06-17 shizhenshan
  7. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a04329344470, createdName=zlawrance, createdTime=Thu Jan 29 07:41:00 CST 2015, time=2015-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020144, encodeId=e899202014448, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Sep 10 08:41:00 CST 2015, time=2015-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661515, encodeId=706d1661515dd, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Thu Sep 03 08:41:00 CST 2015, time=2015-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974589, encodeId=4b4119e458991, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Thu Jun 11 18:41:00 CST 2015, time=2015-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860986, encodeId=8af71860986cb, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Wed Jun 17 14:41:00 CST 2015, time=2015-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491715, encodeId=8a601491e1544, content=<a href='/topic/show?id=130a8158305' target=_blank style='color:#2F92EE;'>#肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81583, encryptionId=130a8158305, topicName=肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3c98898784, createdName=psybestwish, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531237, encodeId=fae7153123ea1, content=<a href='/topic/show?id=3b5ee633753' target=_blank style='color:#2F92EE;'>#粪肠球菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76337, encryptionId=3b5ee633753, topicName=粪肠球菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f72712226339, createdName=hb2012ye, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1546284, encodeId=bffa15462846d, content=<a href='/topic/show?id=0da528e33ce' target=_blank style='color:#2F92EE;'>#光动力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28733, encryptionId=0da528e33ce, topicName=光动力)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2b6213920685, createdName=luckyshitiancai_42705688, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621513, encodeId=11df162151330, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Sun Jan 18 04:41:00 CST 2015, time=2015-01-18, status=1, ipAttribution=)]
  10. [GetPortalCommentsPageByObjectIdResponse(id=125436, encodeId=e37412543639, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:39:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693131, encodeId=a1a71693131f1, content=<a href='/topic/show?id=22af5495918' target=_blank style='color:#2F92EE;'>#抑菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54959, encryptionId=22af5495918, topicName=抑菌)], attachment=null, authenticateStatus=null, createdAvatar=null, 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