Heart:植入性心脏除颤器对非缺血性心肌病死亡率的作用这么大!

2017-08-08 MedSci MedSci原创

目前,植入式心脏除颤器(ICD)在收缩功能障碍和非缺血性心肌病的有症状患者中的益处仍有争议。近期,一项发表在杂志Heart上的研究进行了系统的综述和荟萃分析,以确定ICD对非缺血性心肌病患者的全因死亡率、心血管死亡率以及心源性猝死的影响。首先,研究者们在2012年发布的荟萃分析以及2012年至2016年的MEDLINE、Embase、PubMed和Cochrane数据库中搜索了引用文献。搜索包括随

目前,植入式心脏除颤器(ICD)在收缩功能障碍和非缺血性心肌病的有症状患者中的益处仍有争议。近期,一项发表在杂志Heart上的研究进行了系统的综述和荟萃分析,以确定ICD对非缺血性心肌病患者的全因死亡率、心血管死亡率以及心源性猝死的影响。首先,研究者们在2012年发布的荟萃分析以及2012年至2016年的MEDLINE、Embase、PubMed和Cochrane数据库中搜索了引用文献。搜索包括随机对照试验(RCT)评估ICD治疗对非缺血性心肌病患者的全因死亡、心血管死亡率以及心源性死亡的影响。另有独立评审员评估研究的合格性,抽象数据和评估偏倚风险一式两份。研究者使用随机效应模型对研究中的相对风险(RR)和风险比(HR)进行Meta分析,推荐等级,评估,开发和评估系统来量化绝对效应和证据质量,I2评估异质性。最终,此项研究确定了6项RCT,其中包括1715例患者,死亡421例。ICD治疗与总体死亡率(HR 0.78,95%CI 0.66〜0.92,I2 = 0%,风险差异4.7%,高质量),心血管死亡率(RR 0.77,95%CI 0.60〜0.98,I2 = 39% ,风险差3.3%

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    2017-08-12 大爰

    学习了谢谢分享!!

    0

  4. 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createdName=achengzhao, createdTime=Sun Feb 25 01:34:00 CST 2018, time=2018-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232764, encodeId=754b232e6408, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Aug 12 08:35:30 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356460, encodeId=ce931356460e1, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1439138, encodeId=92901439138f9, content=<a href='/topic/show?id=8e3a98396f2' target=_blank style='color:#2F92EE;'>#除颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98396, encryptionId=8e3a98396f2, topicName=除颤)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520391, encodeId=08d315203910c, content=<a href='/topic/show?id=7a736264553' target=_blank 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createdName=爆笑小医, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231717, encodeId=7513231e17e5, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Aug 09 08:32:01 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-10 zhaojie88
  5. 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authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1439138, encodeId=92901439138f9, content=<a href='/topic/show?id=8e3a98396f2' target=_blank style='color:#2F92EE;'>#除颤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98396, encryptionId=8e3a98396f2, topicName=除颤)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520391, encodeId=08d315203910c, content=<a href='/topic/show?id=7a736264553' target=_blank 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createdName=爆笑小医, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231717, encodeId=7513231e17e5, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Aug 09 08:32:01 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-10 zhouqu_8
  6. [GetPortalCommentsPageByObjectIdResponse(id=1892918, encodeId=f05518929187c, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Sun Mar 18 02:34:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2019085, encodeId=2c11201908557, content=<a href='/topic/show?id=ff23626e3bd' target=_blank style='color:#2F92EE;'>#植入性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62673, encryptionId=ff23626e3bd, topicName=植入性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, 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style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523420, encodeId=bd171523420a7, content=<a href='/topic/show?id=2553e9365a9' target=_blank style='color:#2F92EE;'>#缺血性心肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79365, encryptionId=2553e9365a9, topicName=缺血性心肌病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ec11518906, createdName=huanbaofeng, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), 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createdName=爆笑小医, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231717, encodeId=7513231e17e5, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Aug 09 08:32:01 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-10 jiyangfei
  7. 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style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1523420, encodeId=bd171523420a7, content=<a href='/topic/show?id=2553e9365a9' target=_blank style='color:#2F92EE;'>#缺血性心肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79365, encryptionId=2553e9365a9, topicName=缺血性心肌病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ec11518906, createdName=huanbaofeng, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), 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  8. 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createdName=爆笑小医, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231717, encodeId=7513231e17e5, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Aug 09 08:32:01 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-10 slcumt
  9. 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  10. 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createdName=爆笑小医, createdTime=Thu Aug 10 08:34:00 CST 2017, time=2017-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=231717, encodeId=7513231e17e5, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Wed Aug 09 08:32:01 CST 2017, time=2017-08-09, status=1, ipAttribution=)]
    2017-08-09 李东泽

    很好,不错,以后会多学习

    0