PLos One:SLE女性患者中体力活动和久坐时间与动脉硬化的关联

2018-04-26 xiangting MedSci原创

SLE患者中PA强度水平和久坐时间与动脉硬化无关。

这篇文章目的是研究轻度活动性系统性红斑狼疮(SLE)女性患者中,客观测量的体力活动(PA)强度水平和久坐时间与动脉硬化的关联,并分析符合国际PA指南的参与者与不符合PA指南的患者相比,是否具有较低的动脉硬化。

该研究包括47名SLE女性患者(平均年龄41.2 [标准差13.9]岁),研究前6个月内临床表现和治疗稳定。PA强度水平和久坐时间客观地用三轴加速度计测量。通过脉搏波速度评估动脉硬化,脉搏波速度通过Mobil-O-Graph?24h脉搏波分析监测器评估。

连续≥10分钟的中等到剧烈PA的平均时间为每周135.1±151.8分钟。无论是最初分析还是调整潜在混杂因素后,PA强度水平和久坐时间与动脉硬化均无关联。符合国际PA指南参与者的脉搏波速度不低于不符合PA指南的参与者(b = -0.169; 95%CI:-0.480至0.143; P = 0.280)。

这项研究结果表明,SLE患者中PA强度水平和久坐时间与动脉硬化无关。进一步分析显示符合国际PA指南的SLE患者动脉僵硬程度不低于不符合PA指南的患者。未来需要前瞻性研究以更好地了解SLE患者中PA和久坐时间与动脉僵硬度的关系。

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    2018-04-26 王秀

    学习了.涨知识了!

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