锂能阻止阿尔茨海默症的进展吗?

2020-01-27 Allan MedSci原创

时至今日,科学界仍在争论锂疗法在治疗阿尔茨海默症中的价值,这很大程度上是由于以下事实:由于迄今为止收集的信息是使用多种不同的方法、条件、制剂、治疗时间和剂量获得的,因此难以横向比较。

时至今日,科学界仍在争论锂疗法在治疗阿尔茨海默症中的价值,这很大程度上是由于以下事实:由于迄今为止收集的信息是使用多种不同的方法、条件、制剂、治疗时间和剂量获得的,因此难以横向比较。另外,用高剂量锂持续治疗会带来许多严重的不利影响,这使得患者无法使用这种方法进行长期治疗,特别是老年患者。

然而,加拿大麦吉尔大学药理学Claudio Cuello博士领导的一项研究表明,当以促进大脑通过的配方给药时,锂的剂量可比目前针对情绪障碍所规定的剂量低2倍,既可以制止阿尔茨海默症晚期病征(如淀粉样斑块),又可以恢复丧失的认知能力。研究结果最近发表《Journal of Alzheimer's Disease》上。


原始出处:

https://www.firstwordpharma.com/node/1696101?tsid=4

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    2020-09-25 DEXTER3150
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