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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1906 1
1907 2
1909 1
1910 1
1911 5
1912 3
1913 5
1914 6
1916 6
1917 5
1919 1
1920 4
1921 1
1922 8
1923 5
1924 4
1926 7
1927 1
1928 7
1929 3
1930 2
1931 4
1932 8
1933 6
1934 3
1935 2
1936 5
1937 4
1938 3
1939 7
1940 3
1941 2
1942 4
1945 7
1946 21
1947 41
1948 47
1949 33
1950 56
1951 60
1952 89
1953 129
1954 163
1955 179
1956 184
1957 214
1958 284
1959 300
1960 370
1961 479
1962 613
1963 881
1964 1752
1965 5061
1966 4983
1967 3484
1968 3388
1969 4332
1970 4884
1971 5024
1972 4321
1973 4645
1974 5009
1975 6660
1976 6494
1977 7101
1978 7272
1979 7401
1980 8155
1981 8513
1982 9406
1983 10276
1984 11557
1985 12579
1986 12815
1987 13432
1988 14146
1989 16152
1990 17422
1991 17531
1992 18029
1993 19009
1994 19066
1995 19456
1996 19265
1997 19744
1998 20247
1999 20967
2000 21806
2001 22430
2002 23312
2003 24692
2004 26262
2005 28852
2006 30185
2007 30931
2008 32091
2009 33440
2010 36846
2011 39284
2012 42576
2013 44534
2014 45549
2015 47111
2016 47416
2017 48788
2018 50418
2019 52664
2020 55350
2021 55562
2022 49169
2023 45877
2024 17496

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1,238,978 results

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Page 1
In Vitro Models to Study Human Lung Development, Disease and Homeostasis.
Miller AJ, Spence JR. Miller AJ, et al. Physiology (Bethesda). 2017 May;32(3):246-260. doi: 10.1152/physiol.00041.2016. Physiology (Bethesda). 2017. PMID: 28404740 Free PMC article. Review.
However, animal models are not always fully able to recapitulate human lung development and disease, highlighting an area where in vitro models of the human lung can compliment animal models to further understanding of critical developmental and pathological mechani …
However, animal models are not always fully able to recapitulate human lung development and disease, highlighting an area where in …
Flow-enhanced vascularization and maturation of kidney organoids in vitro.
Homan KA, Gupta N, Kroll KT, Kolesky DB, Skylar-Scott M, Miyoshi T, Mau D, Valerius MT, Ferrante T, Bonventre JV, Lewis JA, Morizane R. Homan KA, et al. Nat Methods. 2019 Mar;16(3):255-262. doi: 10.1038/s41592-019-0325-y. Epub 2019 Feb 11. Nat Methods. 2019. PMID: 30742039 Free PMC article.
Here we report an in vitro method for culturing kidney organoids under flow on millifluidic chips, which expands their endogenous pool of endothelial progenitor cells and generates vascular networks with perfusable lumens surrounded by mural cells. ... …
Here we report an in vitro method for culturing kidney organoids under flow on millifluidic chips, which expands their endogen …
Spherical cancer models in tumor biology.
Weiswald LB, Bellet D, Dangles-Marie V. Weiswald LB, et al. Neoplasia. 2015 Jan;17(1):1-15. doi: 10.1016/j.neo.2014.12.004. Neoplasia. 2015. PMID: 25622895 Free PMC article. Review.
Three-dimensional (3D) in vitro models have been used in cancer research as an intermediate model between in vitro cancer cell line cultures and in vivo tumor. Spherical cancer models represent major 3D in vitro models that have been desc …
Three-dimensional (3D) in vitro models have been used in cancer research as an intermediate model between in vitro …
Advances in predictive in vitro models of drug-induced nephrotoxicity.
Soo JY, Jansen J, Masereeuw R, Little MH. Soo JY, et al. Nat Rev Nephrol. 2018 Jun;14(6):378-393. doi: 10.1038/s41581-018-0003-9. Nat Rev Nephrol. 2018. PMID: 29626199 Free PMC article. Review.
In vitro screens for nephrotoxicity are currently poorly predictive of toxicity in humans. Although the functional proteins that are expressed by nephron tubules and mediate drug susceptibility are well known, current in vitro cellular models po …
In vitro screens for nephrotoxicity are currently poorly predictive of toxicity in humans. Although the functional proteins th …
Stabilizing hematopoietic stem cells in vitro.
Wilkinson AC, Nakauchi H. Wilkinson AC, et al. Curr Opin Genet Dev. 2020 Oct;64:1-5. doi: 10.1016/j.gde.2020.05.035. Epub 2020 Jun 20. Curr Opin Genet Dev. 2020. PMID: 32570191 Free PMC article. Review.
However, as a rare bone marrow cell population, the characterization and collection of HSCs can often be challenging. This has led to a large search for in vitro culture conditions that support the growth of functional HSCs and the in vitro stabilizati …
However, as a rare bone marrow cell population, the characterization and collection of HSCs can often be challenging. This has led to a larg …
Mimicking the Articular Joint with In Vitro Models.
Piluso S, Li Y, Abinzano F, Levato R, Moreira Teixeira L, Karperien M, Leijten J, van Weeren R, Malda J. Piluso S, et al. Trends Biotechnol. 2019 Oct;37(10):1063-1077. doi: 10.1016/j.tibtech.2019.03.003. Epub 2019 Apr 16. Trends Biotechnol. 2019. PMID: 31000204 Review.
Treating joint diseases remains a significant clinical challenge. Conventional in vitro cultures and animal models have been helpful, but suffer from limited predictive power for the human response. ...However, the intricate structure of the joint microenvironment a …
Treating joint diseases remains a significant clinical challenge. Conventional in vitro cultures and animal models have been h …
Critical Assessment of In Vitro and In Vivo Models to Study Marrow Adipose Tissue.
Reagan MR. Reagan MR. Curr Osteoporos Rep. 2020 Apr;18(2):85-94. doi: 10.1007/s11914-020-00569-4. Curr Osteoporos Rep. 2020. PMID: 32124181 Free PMC article. Review.
PURPOSE OF THE REVIEW: The purpose of this review is to describe the in vitro and in vivo methods that researchers use to model and investigate bone marrow adipocytes (BMAds). ...Recently, researchers have developed in vitro and in vivo models to study …
PURPOSE OF THE REVIEW: The purpose of this review is to describe the in vitro and in vivo methods that researchers use to mode …
Analysis of tumour responses by excision and in vitro assay of cellular clonogenic capacity.
Barendsen GW. Barendsen GW. Br J Cancer Suppl. 1980 Apr;4:209-16. Br J Cancer Suppl. 1980. PMID: 7000122 Free PMC article. Review.
A review is presented of the advantages and problems associated with the use of in vitro assays of cellular clonogenic capacity when used to analyse responses of tumours treated in vivo, either with radiation or chemotherapeutic agents. ...(3) Are the propert …
A review is presented of the advantages and problems associated with the use of in vitro assays of cellular clonogenic …
A Brief Review of In Vitro Models for Injury and Regeneration in the Peripheral Nervous System.
Varier P, Raju G, Madhusudanan P, Jerard C, Shankarappa SA. Varier P, et al. Int J Mol Sci. 2022 Jan 13;23(2):816. doi: 10.3390/ijms23020816. Int J Mol Sci. 2022. PMID: 35055003 Free PMC article. Review.
In addition to in vivo and mathematical models, in vitro axonal injury models provide a simple, robust, and reductionist platform to partially understand nerve injury pathogenesis and regeneration. In recent years, there have been several advances related to in …
In addition to in vivo and mathematical models, in vitro axonal injury models provide a simple, robust, and reductionist platf …
Cell sources for in vitro human liver cell culture models.
Zeilinger K, Freyer N, Damm G, Seehofer D, Knöspel F. Zeilinger K, et al. Exp Biol Med (Maywood). 2016 Sep;241(15):1684-98. doi: 10.1177/1535370216657448. Epub 2016 Jul 5. Exp Biol Med (Maywood). 2016. PMID: 27385595 Free PMC article. Review.
In vitro liver cell culture models are gaining increasing importance in pharmacological and toxicological research. ...This review gives an overview of the major human cell sources under investigation for in vitro liver cell culture models, including p …
In vitro liver cell culture models are gaining increasing importance in pharmacological and toxicological research. ...This re …
1,238,978 results
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