Loss of UBE2S causes meiosis I arrest with normal spindle assembly checkpoint dynamics in mouse oocytes.
Sun SM, Zhao BW, Li YY, Liu HY, Xu YH, Yang XM, Guo JN, Ouyang YC, Weng CJ, Guan YC, Sun QY, Wang ZB.
Sun SM, et al.
Development. 2024 Mar 15;151(6):dev202285. doi: 10.1242/dev.202285. Epub 2024 Mar 28.
Development. 2024.
PMID: 38546043
APC/C has been extensively studied, but the functions of UBE2S in oocyte maturation and mouse fertility are not clear. In this study, we used Ube2s knockout mice to explore the role of UBE2S in mouse oocytes. ...In conclusion, our findings reveal an indispensable regulator …
APC/C has been extensively studied, but the functions of UBE2S in oocyte maturation and mouse fertility are not clear. In this study, …