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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 1
1996 1
2000 2
2003 1
2004 5
2005 2
2006 4
2007 4
2008 1
2009 1
2010 5
2011 5
2012 3
2013 5
2014 11
2015 10
2016 10
2017 10
2018 14
2019 23
2020 45
2021 37
2022 33
2023 32
2024 12

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269 results

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Page 1
NFX1, Its Isoforms and Roles in Biology, Disease and Cancer.
Chintala S, Katzenellenbogen RA. Chintala S, et al. Biology (Basel). 2021 Mar 30;10(4):279. doi: 10.3390/biology10040279. Biology (Basel). 2021. PMID: 33808060 Free PMC article. Review.
In 1989, two NFX1 protein products were identified as nuclear proteins with the ability to bind to X-box cis-elements. Since that publication, the NFX1 gene and its homologs have been identified, from yeast to humans. ...
In 1989, two NFX1 protein products were identified as nuclear proteins with the ability to bind to X-box cis-elements. Since that pub …
The Nuclear Envelope in Lipid Metabolism and Pathogenesis of NAFLD.
Östlund C, Hernandez-Ono A, Shin JY. Östlund C, et al. Biology (Basel). 2020 Oct 15;9(10):338. doi: 10.3390/biology9100338. Biology (Basel). 2020. PMID: 33076344 Free PMC article. Review.
Emerging evidence points toward that the nuclear lamins and nuclear membrane-associated proteins are involved in lipid metabolism and homeostasis. We review published reports that link these nuclear envelope proteins to lipid metabolism. In particular, we foc …
Emerging evidence points toward that the nuclear lamins and nuclear membrane-associated proteins are involved in lipid metabol …
Nuclear Lamins: Key Proteins for Embryonic Development.
Paul JC, Fulka H. Paul JC, et al. Biology (Basel). 2022 Jan 27;11(2):198. doi: 10.3390/biology11020198. Biology (Basel). 2022. PMID: 35205065 Free PMC article. Review.
Lamins are essential components of the nuclear envelope and have been studied for decades due to their involvement in several devastating human diseases, the laminopathies. Despite intensive research, the molecular basis behind the disease state remains mostly unclear with …
Lamins are essential components of the nuclear envelope and have been studied for decades due to their involvement in several devasta …
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death.
Martínez-Morcillo FJ, Cantón-Sandoval J, Martínez-Navarro FJ, Cabas I, Martínez-Vicente I, Armistead J, Hatzold J, López-Muñoz A, Martínez-Menchón T, Corbalán-Vélez R, Lacal J, Hammerschmidt M, García-Borrón JC, García-Ayala A, Cayuela ML, Pérez-Oliva AB, García-Moreno D, Mulero V. Martínez-Morcillo FJ, et al. PLoS Biol. 2021 Nov 8;19(11):e3001455. doi: 10.1371/journal.pbio.3001455. eCollection 2021 Nov. PLoS Biol. 2021. PMID: 34748530 Free PMC article.
Consistently, an aberrant induction of NAMPT and PARP activity, together with AIFM1 nuclear translocation, was observed in lesional skin from psoriasis patients. ...
Consistently, an aberrant induction of NAMPT and PARP activity, together with AIFM1 nuclear translocation, was observed in lesional s …
New Insights into Cellular Functions of Nuclear Actin.
Kloc M, Chanana P, Vaughn N, Uosef A, Kubiak JZ, Ghobrial RM. Kloc M, et al. Biology (Basel). 2021 Apr 7;10(4):304. doi: 10.3390/biology10040304. Biology (Basel). 2021. PMID: 33916969 Free PMC article. Review.
With the development of more sophisticated imaging and analytical techniques, it became clear that nuclear actin plays a crucial role in shaping the chromatin, genomic, and epigenetic landscape, transcriptional regulation, and DNA repair. ...Here, we discuss some of …
With the development of more sophisticated imaging and analytical techniques, it became clear that nuclear actin plays a cruci …
Hmga2 protein loss alters nuclear envelope and 3D chromatin structure.
Divisato G, Chiariello AM, Esposito A, Zoppoli P, Zambelli F, Elia MA, Pesole G, Incarnato D, Passaro F, Piscitelli S, Oliviero S, Nicodemi M, Parisi S, Russo T. Divisato G, et al. BMC Biol. 2022 Aug 2;20(1):171. doi: 10.1186/s12915-022-01375-3. BMC Biol. 2022. PMID: 35918713 Free PMC article.
Hmga2 ChIP-seq confirmed that this protein preferentially binds to the chromatin regions associated with nuclear lamina. Starting from this observation, we demonstrated that nuclear lamina underwent severe alterations when Hmga2 KO or KD cells were induced to exit f …
Hmga2 ChIP-seq confirmed that this protein preferentially binds to the chromatin regions associated with nuclear lamina. Starting fro …
Nuclear Molecular Imaging of Disease Burden and Response to Treatment for Cardiac Amyloidosis.
Zhao M, Calabretta R, Yu J, Binder P, Hu S, Hacker M, Li X. Zhao M, et al. Biology (Basel). 2022 Sep 24;11(10):1395. doi: 10.3390/biology11101395. Biology (Basel). 2022. PMID: 36290299 Free PMC article. Review.
Transthyretin protein (TTR) and light chain (AL) amyloidosis are the most common types of cardiac amyloidosis. Radionuclide bone scintigraphy has recently become the most common non-invasive test for the diagnosis of TTR-CA but is of limited value for the diagnosis of AL-C …
Transthyretin protein (TTR) and light chain (AL) amyloidosis are the most common types of cardiac amyloidosis. Radionuclide bone scin …
Fascin in Cell Migration: More Than an Actin Bundling Protein.
Lamb MC, Tootle TL. Lamb MC, et al. Biology (Basel). 2020 Nov 17;9(11):403. doi: 10.3390/biology9110403. Biology (Basel). 2020. PMID: 33212856 Free PMC article. Review.
These non-canonical functions include regulating the activity of other actin-binding proteins, binding to and regulating microtubules, mediating mechanotransduction to the nucleus via interaction with the Linker of the Nucleoskeleton and Cytoskeleton (LINC) Complex, and localizin …
These non-canonical functions include regulating the activity of other actin-binding proteins, binding to and regulating microtubules, media …
New Perspectives on the Role of Nuclear Proteases in Cell Death Pathways.
Frolova AS, Chepikova OE, Deviataikina AS, Solonkina AD, Zamyatnin AA Jr. Frolova AS, et al. Biology (Basel). 2023 May 31;12(6):797. doi: 10.3390/biology12060797. Biology (Basel). 2023. PMID: 37372081 Free PMC article. Review.
Multiple factors can trigger cell death via various pathways, and nuclear proteases have emerged as essential regulators of these processes. While certain nuclear proteases have been extensively studied and their mechanisms of action are well understood, others rema …
Multiple factors can trigger cell death via various pathways, and nuclear proteases have emerged as essential regulators of these pro …
Unravelling the Network of Nuclear Matrix Metalloproteinases for Targeted Drug Design.
Frolova AS, Petushkova AI, Makarov VA, Soond SM, Zamyatnin AA Jr. Frolova AS, et al. Biology (Basel). 2020 Dec 19;9(12):480. doi: 10.3390/biology9120480. Biology (Basel). 2020. PMID: 33352765 Free PMC article. Review.
A growing number of these proteins are being found to exist in the nuclei of both healthy and tumor cells, thus highlighting their localization as having a genuine purpose in cellular homeostasis. The mechanism underlying nuclear transport and the effects of MMP nuclear …
A growing number of these proteins are being found to exist in the nuclei of both healthy and tumor cells, thus highlighting their localizat …
269 results