Free Radical Biology and Medicine is an international, interdisciplinary publication encompassing chemical, biochemical, physiological, pathological, pharmacological, toxicological and medical approaches to free-radical research. The Journal publishes original, peer-reviewed articles dealing with all aspects of free radical production, metabolism, damage, protection, and measurement in biological systems. Ranked first in its field by ISI, this journal continues to publish the highest quality material in free radical research. In 1999, Free Radical Biology & Medicine will increase in frequency to 24 issues per year.