期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (4)
Metabolic engineering of microbial hosts for the production of heterologous metabolites and biochemicals is an enabling technology to generate meaning......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (6)
Targeted genome disruptions and single-nucleotide conversions with the CRISPR/Cas system have greatly facilitated the development of gene therapy, bas......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (7)
Y Chloroplasts are attractive platforms for synthetic biology applications since they are capable of driving very high levels of transgene expression,......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (5)
Various antibody-redirected immunotherapeutic approaches, including antibody-drug conjugates (ADCs), bispecific antibodies (bsAbs), and chimeric antig......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (1)
1,5-Pentanediol (1,5-PDO) is an important C5 building block for the synthesis of different value-added polyurethanes and polyesters. However, no natur......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (5)
APOBEC3A (A3A) is a cytidine deaminase involved in innate immune response and is able to catalyze deamination on both DNA and RNA substrates. It was u......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (4)
Herein, we constructed a new type of hydrogel based artificial cells supporting long-lived protein synthesis, post-translational modification, and gen......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (5)
Transcription-factor-based biosensors (TFBs) are often used for metabolite detection, adaptive evolution, and metabolic flux control. However, designi......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (1)
Microbial synthesis of chemicals typically requires the redistribution of metabolic flux toward the synthesis of targeted products. Dynamic control is......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (5)
CRISPR/Cas9-mediated base editors, based on cytidine deaminase or adenosine deaminase, are emerging genetic technologies that facilitate genomic manip......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (7)
Corynebacterium glutamicum is an important industrial workhorse for the production of amino acids and other chemicals. However, the engineering of C. ......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (6)
With the flexibility to fold into complex structures, RNA is well-suited to act as a cellular sensor to recognize environmental fluctuations and respo......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (7)
The dynamic regulation of metabolic pathways is based on changes in external signals and endogenous changes in gene expression levels and has extensiv......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (6)
Efficient transcription termination relying on intrinsic terminators is critical to maintain cell fitness by avoiding unwanted read-through in bacteri......
期刊： ACS SYNTHETIC BIOLOGY, 2021; 10 (4)
Episomal plasmids are crucial expression tools for recombinant protein production and genome editing. In Saccharomyces cerevisiae, 2-mu m artificial p......
