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YAP/TAZ get a STING in the tail

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (9)

Sladitschek-Martens show that reduced activity of key cellular mechanosensors, transcription co-activators YAP/TAZ, is an important driver of ageing o......

JIF:32.827

Cell cycle control in cancer

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (1)

This Review discusses our current understanding of cell cycle regulation, the functions of cell cycle checkpoints and how disruption of these finely t......

JIF:32.827

FROM TRANS-SPLICING DISCOVERY AND ONWARDS, TRYPANOSOMES LEAD THE WAY

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (6)

Viegas and Figueiredo tell us how, among several molecular and biochemical discoveries, RNA trans-splicing was discovered in trypanosomes.

JIF:32.827

Ubiquitin ligases: guardians of mammalian development

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (5)

Mammalian development demands precision. Millions of molecules must be properly located in temporal order, and their function regulated, to orchestrat......

JIF:32.827

Plant hormone regulation of abiotic stress responses

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (10)

Plant hormones are signalling compounds that regulate crucial aspects of growth, development and environmental stress responses. Abiotic stresses, suc......

JIF:32.827

Reactive oxygen species signalling in plant stress responses

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (10)

Reactive oxygen species (ROS) are key signalling molecules that enable cells to rapidly respond to different stimuli. In plants, ROS play a crucial ro......

JIF:32.827

Reassessing the relationship between mRNA levels and protein abundance in exercised skeletal muscles

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (12)

A long-standing paradigm in molecular biology assumes a direct relationship between increases in mRNA levels and the abundance of the proteins they en......

JIF:32.827

Pioneer factors as master regulators of the epigenome and cell fate

期刊: NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2022; 23 (7)

Pioneer factors are transcription factors with the unique ability to initiate opening of closed chromatin. The stability of cell identity relies on ro......

JIF:32.827

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