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Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro

期刊: Scientific Reports, 2017; 7 ( )

Club cells are known to function as regional progenitor cells to repair the bronchiolar epithelium in response to lung damage. By lineage tracing in m......

JIF:4.12

Evaluation of 10 SLE susceptibility loci in Asian populations, which were initially identified in European populations

期刊: Scientific Reports, 2017; 7 ( )

Ten novel loci have been found to be associated with systemic lupus erythematosus (SLE) susceptibility by a recent genome-wide association study condu......

JIF:4.12

Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells

期刊: Scientific Reports, 2017; 7 ( )

The actin cytoskeleton is an attractive target for bacterial toxins. The ADP-ribosyltransferase TccC3 from the insect bacterial pathogen Photorhabdus ......

JIF:4.12

Physiological performance of the intertidal Manila clam (Ruditapes philippinarum) to long-term daily rhythms of air exposure

期刊: Scientific Reports, 2017; 7 ( )

Intertidal organisms, especially the sessile species, often experience long-term periodic air exposure during their lives. Learning the biochemical an......

JIF:4.12

A Circular Polarizer with Beamforming Feature Based on Frequency Selective Surfaces

期刊: Scientific Reports, 2017; 7 ( )

We propose a circular polarizer with beamforming features based on frequency selective surface (FSS), in which a modified anchor-shaped unit cell is u......

JIF:4.12

Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro

期刊: Scientific Reports, 2017; 7 ( )

Thiazolidinediones (TZD) function as potent anti-diabetic drugs through their direct action on the nuclear receptor peroxisome proliferator-activated ......

JIF:4.12

Protective effects of recombinant human cytoglobin against chronic alcohol-induced liver disease in vivo and in vitro

期刊: Scientific Reports, 2017; 7 ( )

Alcoholic liver disease (ALD) is an important worldwide public health issue with no satisfying treatment available since now. Here we explore the effe......

JIF:4.12

Low level of swiprosin-1/EFhd2 in vestibular nuclei of spontaneously hypersensitive motion sickness mice

期刊: Scientific Reports, 2017; 7 ( )

Susceptibility to motion sickness (MS) varies considerably among humans. However, the cause of such variation is unclear. Here, we used a classical ge......

JIF:4.12

Functional characterization of a gibberellin receptor and its application in alfalfa biomass improvement

期刊: Scientific Reports, 2017; 7 ( )

Bioactive gibberellins (GAs) are essential phytohormones involved in the regulation of many aspects of plant development. GA receptors are crucial in ......

JIF:4.12

A de novo deletion mutation in SOX10 in a Chinese family with Waardenburg syndrome type 4

期刊: Scientific Reports, 2017; 7 ( )

Waardenburg syndrome type 4 (WS4) or Waardenburg-Shah syndrome is a rare genetic disorder with a prevalence of <1/1,000,000 and characterized by th......

JIF:4.12

An Oxidoreductase AioE is Responsible for Bacterial Arsenite Oxidation and Resistance

期刊: Scientific Reports, 2017; 7 ( )

Previously, we found that arsenite (As-III) oxidation could improve the generation of ATP/NADH to support the growth of Agrobacterium tumefaciens GW4.......

JIF:4.12

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart

期刊: Scientific Reports, 2017; 7 ( )

Hyperglycemia (HG) stimulates the production of reactive oxygen species in the heart through activation of NADPH oxidase 2 (NOX2). This production is ......

JIF:4.12

RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP

期刊: Scientific Reports, 2017; 7 ( )

Multifunctional RNA helicase DDX3 participates in HCV infection, one of the major causes of hepatic steatosis. Here, we investigated the role of DDX3 ......

JIF:4.12

One-Pot Green Synthesis of Graphene Nanosheets Encapsulated Gold Nanoparticles for Sensitive and Selective Detection of Dopamine

期刊: Scientific Reports, 2017; 7 ( )

We report a simple new approach for green preparation of gallic acid supported reduced graphene oxide encapsulated gold nanoparticles (GA-RGO/AuNPs) v......

JIF:4.12

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study

期刊: Scientific Reports, 2017; 7 ( )

Cardiovascular diseases due to atherosclerosis are the leading cause of death globally. We aimed to investigate the potentially altered gene and pathw......

JIF:4.12

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