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Epigenetic Reprogramming in Early Animal Development

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2022; 14 (6)

Dramatic nuclear reorganization occurs during early development to convert terminally differentiated gametes to a totipotent zygote, which then gives ......

JIF:9.59

Role of Two-Pore Channels in Embryonic Development and Cellular Differentiation

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2020; 12 (1)

Since the identification of nicotinic acid adenine dinucleotide phosphate (NAADP) and its putative target, the two-pore channel (TPC), the NAADP/TPC/C......

The Formation of Coronary Vessels in Cardiac Development and Disease

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2020; 12 (5)

Understanding how coronary blood vessels form and regenerate during development and progression of cardiac diseases will shed light on the development......

Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2019; 11 (1)

Precursor messenger RNA (pre-mRNA) splicing is executed by the spliceosome. In the past 3 years, cryoelectron microscopy (cryo-EM) structures have bee......

JIF:9.11

Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2018; 10 (7)

RNA G-quadruplex (rG4) secondary structures are proposed to play key roles in fundamental biological processes that include the modulation of transcri......

JIF:9.11

Polarized Exocytosis

期刊: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2017; 9 (12)

Polarized exocytosis is generally considered as the multistep vesicular trafficking process in which membrane-bounded carriers are transported from th......

JIF:9.25

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