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Demethyleneberberine promotes apoptosis and suppresses TGF-beta/Smads induced EMT in the colon cancer cells HCT-116

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

Colorectal cancer (CRC) is one of the most common malignant tumours in the world. Recent reports have revealed natural products displayed inhibition o......

Autophagy in tooth: Physiology, disease and therapeutic implication

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

Autophagy is an evolutionarily conserved cellular process, in which damaged organelles and proteins are engulfed in autophagic vesicles and subsequent......

S100A6 represses Calu-6 lung cancer cells growth via inhibiting cell proliferation, migration, invasion and enhancing apoptosis

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

S100 calcium binding protein A6 (S100A6) has been reported to involve in many kinds of cancers through regulating intracellular calcium homeostasis. P......

Abnormal neuronal damage and inflammation in the hippocampus of kainic acid-induced epilepsy mice

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

In this study, we established a mouse model of epilepsy and analysed abnormal neuronal damage and inflammation in the hippocampus of mice with kainic ......

The effects of biophysical stimulation on osteogenic differentiation and the mechanisms from ncRNAs

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

Ample proof showed that non-coding RNAs (ncRNAs) play a crucial role in proliferation and differentiation of osteoblasts and bone marrow stromal cells......

Biological insights into the rapid tissue regeneration of freshwater crayfish and crustaceans

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2021; 39 (6)

The freshwater crayfish is capable of regenerating limbs, following autotomy, injury and predation. In arthropod species, regeneration and moulting ar......

Melatonin alleviates d-galactose-decreased hyaluronic acid production in synovial membrane cells via Sirt1 signalling

期刊: CELL BIOCHEMISTRY AND FUNCTION, ; ()

Hyaluronic acid (HA) exerts a critical role in the lubricating and buffering properties of synovial fluid in joints. The production of HA is regulated......

Molecular structure, gene expression and functional role of WFDC1 in angiogenesis and cancer

期刊: CELL BIOCHEMISTRY AND FUNCTION, ; ()

Whey acidic proteins (WAP) perform a diverse range of important biological functions, including proteinase activity, calcium transport and bacterial g......

TTP488 ameliorates NLRP3-associated inflammation, viability, apoptosis, and ROS production in an Alzheimer's disease cell model by mediating the JAK1/STAT3/NF kappa B/IRF3 pathway

期刊: CELL BIOCHEMISTRY AND FUNCTION, ; ()

Alzheimer's disease (AD), the most prevalent dementia, is identified as a neurodegenerative disease arising from a degenerative disturbance in the cen......

WWP2 ameliorates acute kidney injury by mediating p53 ubiquitylation and degradation

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2020; 38 (6)

E3 ubiquitin ligase gene, WWP2, is associated with acute kidney injury (AKI). This research was conducted to explore the role of WWP2 in AKI. AKI cell......

Circular RNA has_circ_0000527 participates in proliferation, invasion and migration of retinoblastoma cells via miR-646/BCL-2 axis

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2020; 38 (8)

Retinoblastoma (RB) is one of the most common primary intraocular malignancies in children. Emerging researches have shown that circular RNAs (circRNA......

DGUOK-AS1 promotes cell proliferation in cervical cancer via acting as a ceRNA of miR-653-5p

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2020; 38 (7)

Cervical cancer (CC) holds the second highest incidence and is the fourth dominating cause of cancer-induced death in women. It has been widely accept......

Betulinic acid triggers apoptosis and inhibits migration and invasion of gastric cancer cells by impairing EMT progress

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2020; 38 (6)

Gastric cancer (GC) is one of the most prevalent types of malignancies. Betulinic acid (BA) is a natural pentacyclic triterpene with a lupine structur......

CASC5 is a potential tumour driving gene in lung adenocarcinoma

期刊: CELL BIOCHEMISTRY AND FUNCTION, 2020; 38 (6)

Previous studies have shown that cancer susceptibility candidate 5 (CASC5) plays important roles in several types of cancer. But its expression and cl......

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