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Exosome miR-23a-3p from Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-Regulating KLF3-Activated CCNL2 Transcription

期刊: DEVELOPMENTAL NEUROSCIENCE, 2022; 44 (3)

Background: Spinal cord ischemia/reperfusion injury (SCIRI) is usually caused by spinal surgery or aortic aneurysm surgery and can eventually lead to ......

JIF:2.662

Repeated Neonatal Exposure to Sevoflurane Induces Age-Dependent Impairments in Cognition and Synaptic Plasticity in Mice

期刊: DEVELOPMENTAL NEUROSCIENCE, 2022; 44 (3)

Background: Sevoflurane is a volatile anesthetic that is widely used in pediatric anesthesia due to its low toxicity. However, whether neonatal exposu......

JIF:2.662

Bioinformatic Analysis Reveals the Distinct Role of 5'UTR-Specific m6A RNA Modification in Mice Developing Cerebral Cortices

期刊: DEVELOPMENTAL NEUROSCIENCE, 2022; 44 (2)

N6-methyladenosine (m6A) abundantly exists in the cerebral cortex and is emerging as an essential factor in cortical development and function. As the ......

JIF:2.662

A Novel Variant of the KIF11 Gene, c.2922G > T, Is Associated with Microcephaly by Affecting RNA Splicing

期刊: DEVELOPMENTAL NEUROSCIENCE, 2022; 44 (2)

Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR) is an inherited disorder characterized by severe microcephal......

JIF:2.662

Circ-Ctnnb1 Regulates Neuronal Injury in Spinal Cord Injury through the Wnt/beta-Catenin Signaling Pathway

期刊: DEVELOPMENTAL NEUROSCIENCE, 2022; 44 (3)

Study Design: Spinal cord injury (SCI) rat model and cell model were established for in vivo and in vitro experiments. Functional assays were utilized......

JIF:2.662

Aluminum Microcomb Electrodes on Silicon Wafer for Detecting Val66Met Polymorphism in Brain-Derived Neurotrophic Factor

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 43 (1)

Objective: Brain-derived neurotrophic factor (BDNF) dysregulation is widely related with various psychiatric and neurological disorders, including sch......

Zebrafish Minichromosome Maintenance Protein 5 Gene Regulates the Development and Migration of Facial Motor Neurons via Fibroblast Growth Factor Signaling

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 43 (2)

Minichromosome maintenance protein 5 (MCM5), a member of the microchromosomal maintenance protein family, plays an important role in the initiation an......

Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 43 (2)

An adverse maternal environment (AME) predisposes adult offspring toward cognitive impairment in humans and mice. However, the underlying mechanisms r......

Long Noncoding RNA SPRY4-IT1 Modulates Ketamine-Induced Neurotoxicity in Human Embryonic Stem Cell-Derived Neurons through EZH2

期刊: DEVELOPMENTAL NEUROSCIENCE, ; ()

Objective: This study aimed to investigate whether long noncoding RNA sprouty receptor tyrosine kinase signaling antagonist 4-intronic transcript 1 (S......

TrkC Overexpression Protects Sevoflurane-Induced Neurotoxicity in Human Induced Pluripotent Stem Cell-Derived Neurons

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (2-4)

Background: Inhaled anesthetic sevoflurane (SEVO) may induce cortical neurotoxicity and memory dysfunction in both animals and humans. In this study, ......

miR-325-3p Protects Neurons from Oxygen-Glucose Deprivation and Reoxygenation Injury via Inhibition of RIP3

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (2-4)

Objective: Recent reports have corroborated that micro-RNAs (miRs) are related to the pathological changes of cerebral ischemia-reperfusion (CIR) indu......

The Clinical Significance of miR-135b-5p and Its Role in the Proliferation and Apoptosis of Hippocampus Neurons in Children with Temporal Lobe Epilepsy

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (5-6)

Temporal lobe epilepsy (TLE) is the most familiar localized epilepsy in children. MicroRNAs (miRNAs) are essential for the inhibition or promotion of ......

The Role of Ninjurin1 and Its Impact beyond the Nervous System

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (5-6)

Ninjurin1 (Ninj1) is a double-transmembrane cell surface protein that could promote nerve regeneration in the process of the peripheral nervous system......

FGF3 from the Hypothalamus Regulates the Guidance of Thalamocortical Axons

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (5-6)

Thalamus is an important sensory relay station: afferent sensory information, except olfactory signals, is transmitted by thalamocortical axons (TCAs)......

The Eya1 Phosphatase Mediates Shh-Driven Symmetric Cell Division of Cerebellar Granule Cell Precursors

期刊: DEVELOPMENTAL NEUROSCIENCE, 2021; 42 (5-6)

During neural development, stem and precursor cells can divide either symmetrically or asymmetrically. The transition between symmetric and asymmetric......

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