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C-peptide ameliorates high glucose-induced podocyte dysfunction through the regulation of the Notch and TGF-beta signaling pathways

期刊: PEPTIDES, 2021; 142 ()

The podocyte is one of the main components of the glomerular filtration barrier in the kidney, and its injury may contribute to proteinuria, glomerulo......

Angiotensin-(1-7) protects against sepsis-associated left ventricular dysfunction induced by lipopolysaccharide

期刊: PEPTIDES, 2021; 144 ()

Sepsis-induced myocardial dysfunction is a major cause of death. The present study explored whether angiotensin (Ang)-(1-7), an important biologically......

CCHamide2-receptor regulates feeding behavior in the pea aphid, Acyrthosiphon pisum

期刊: PEPTIDES, 2021; 143 ()

Neuropeptide CCHamide-2 is a recently discovered peptide presents in many arthropods and it is the ligand of the CCHamide-2 receptor (CCHa2-R), which ......

Sublancin protects against methicillin-resistant Staphylococcus aureus infection by the combined modulation of innate immune response and microbiota

期刊: PEPTIDES, 2021; 141 ()

Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen responsible for community and hospital bacterial infections. In the present stu......

The incessant increase curve during oral glucose tolerance tests in Chinese adults with type 2 diabetes and its association with gut hormone levels

期刊: PEPTIDES, 2021; 143 ()

Glucose curve shapes during oral glucose tolerance tests (OGTTs) are mainly classified as incessant increase, monophasic and biphasic. Youth with an i......

Relaxin increased blood pressure and sympathetic activity in paraventricular nucleus of hypertensive rats via enhancing oxidative stress

期刊: PEPTIDES, 2021; 141 ()

Relaxin, an ovarian polypeptide hormone, is found in the hypothalamic paraventricular nucleus (PVN) which is an important central integrative site for......

Characterization of four urotensin II receptors (UTS2Rs) in chickens

期刊: PEPTIDES, 2021; 138 ()

Urotensin II receptor (UTS2R) is suggested to mediate the actions of urotensin II (UTS2) and UTS2-related peptide (URP, also called UTS2B) in mammals.......

Differential expression of motilin receptors on the endothelium of dog gastrointestinal arteries and motilin-induced motilin receptor dependent relaxation of corresponding arteries

期刊: PEPTIDES, 2021; 143 ()

Background: Motilin's role in the regulation of vascular tone and hemodynamic besides gastrointestinal motility is concerned. This study aimed to inve......

Urotensin II induces activation of NLRP3 and pyroptosis through calcineurin in cardiomyocytes

期刊: PEPTIDES, 2021; 144 ()

Cell pyroptosis, a new type of programmed cell death, has been recently reported to play important roles in the development of cardiac remodeling. How......

Effects of neuropeptide Y as a feed additive on stimulating the growth of tilapia ( Oreochromis niloticus ) fed low fish meal diets

期刊: PEPTIDES, 2021; 138 ()

Neuropeptide Y is known to stimulate food intake in fish. In this study, we investigated tilapia NPY (tNPY) both for its effects on the growth of tila......

A synthetic peptide AWRK6 ameliorates metabolic associated fatty liver disease: involvement of lipid and glucose homeostasis

期刊: PEPTIDES, 2021; 143 ()

Metabolic associated fatty liver disease (MAFLD) is the leading common chronic liver disease affecting more than one-quarter of the population worldwi......

Contribution of the mu opioid receptor and enkephalin to the antinociceptive actions of endomorphin-1 analogs with unnatural amino acid modifications in the spinal cord

期刊: PEPTIDES, 2021; 141 ()

Endomorphin analogs containing unnatural amino acids have demonstrated potent analgesic effects in our previous studies. In the present study, the dif......

Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway

期刊: PEPTIDES, 2021; 144 ()

To evaluate the role of ghrelin in cardiac fibrosis after myocardial infarction (MI) and to investigate the underlying mechanisms of ghrelin-regulated......

(m)RVD-hemopressin (alpha) and (m)VD-hemopressin (alpha) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice

期刊: PEPTIDES, 2021; 136 ()

Dysfunction of cholinergic system plays an important role in disease associated with cognitive blockage, such as Alzheimer's disease (AD). Central adm......

Ghrelin inhibited pressure overload-induced cardiac hypertrophy by promoting autophagy via CaMKK/AMPK signaling pathway

期刊: PEPTIDES, 2021; 136 ()

Ghrelin, a novel gut hormone, has been shown to exert protective effects on cardiac dysfunction and remodeling. However, the underlying mechanisms of ......

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