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Long non-coding RNA ZFAS1 alleviates sepsis-induced myocardial injury via target miR-34b-5p/SIRT1

期刊: INNATE IMMUNITY, 2021; 27 (5)

Long non-coding RNA ZFAS1 is down-regulated in sepsis. However, whether ZFAS1 participates in sepsis-induced cardiomyopathy (SIC) remains largely unkn......

miR-150 and SRPK1 regulate AKT3 expression to participate in LPS-induced inflammatory response

期刊: INNATE IMMUNITY, 2021; 27 (4)

miR-150 was found to target the 3 '-untranslated regions of AKT3, and the AKT pathway was affected by SR protein kinase 1 (SRPK1). However, the expres......

Baicalin attenuates LPS-induced alveolar type II epithelial cell A549 injury by attenuation of the FSTL1 signaling pathway via increasing miR-200b-3p expression

期刊: INNATE IMMUNITY, 2021; 27 (4)

In China, baicalin is the main active component of Scutellaria baicalensis, which has been used in the treatment of inflammation-related diseases, suc......

Protective effects of recombinant 53-kDa protein of Trichinella spiralis on acute lung injury in mice via alleviating lung pyroptosis by promoting M2 macrophage polarization

期刊: INNATE IMMUNITY, 2021; 27 (4)

Trichinella spiralis represents an effective treatment for autoimmune and inflammatory diseases. The effects of recombinant T. spiralis (TS) 53-kDa pr......

Construction and analysis for dys-regulated lncRNAs and mRNAs in LPS-induced porcine PBMCs

期刊: INNATE IMMUNITY, ; ()

Long non-coding RNAs (lncRNAs) are emerging as key regulators in inflammation. However, their functions and profiles in LPS-induced inflammation in pi......

Matrix metalloproteinase-9-1562 C/T polymorphism is associated with the risk of sepsis in a Chinese population: A retrospective study

期刊: INNATE IMMUNITY, ; ()

Matrix metalloproteinase-9 (MMP-9) has been shown to participate in the pathogenesis of sepsis. In this study, we recruited 312 sepsis patients and 41......

Anti-nociceptive effect of Portulaca oleracea L. ethanol extracts attenuated zymosan-induced mouse joint inflammation via inhibition of Nrf2 expression

期刊: INNATE IMMUNITY, ; ()

The aim of this study was to explore the effects of ethanol extracts from Portulaca oleracea L. (ePO) on joint inflammation and to explain the underly......

Small ubiquitin-related modifier 2 affects the intracellular survival of Brucella abortus 2308 by regulating activation of the NF-kappa B pathway

期刊: INNATE IMMUNITY, 2021; 27 (1)

Brucella is a genus of Gram-negative intracellular pathogens that cause animal and human diseases. Brucella survival and replication inside immune cel......

Role of collectin-11 in innate defence against uropathogenic Escherichia coli infection

期刊: INNATE IMMUNITY, 2021; 27 (1)

Classical collectins (surfactant protein A and D) play a significant role in innate immunity and host defence in uropathogenic Escherichia coli (UPEC)......

MiR-30a-5p ameliorates LPS-induced inflammatory injury in human A549 cells and mice via targeting RUNX2

期刊: INNATE IMMUNITY, 2021; 27 (1)

In this study, we aim to investigate the role of miR-30a-5p in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) using LPS-induced A549......

Kinetics of changes in gene and microRNA expression related with muscle inflammation and protein degradation following LPS-challenge in weaned piglets

期刊: INNATE IMMUNITY, 2021; 27 (1)

To test the dynamic changes of the expression of genes and microRNA in the gastrocnemius muscle after LPS challenge, 36 piglets were assigned to a con......

Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice

期刊: INNATE IMMUNITY, 2021; 27 (2)

Increasing evidence indicates that signal transducer and activator of transcription 3 (STAT3), a vital transcription factor, plays crucial roles in th......

Construction and analysis for dys-regulated lncRNAs and mRNAs in LPS-induced porcine PBMCs

期刊: INNATE IMMUNITY, 2021; 27 (2)

Long non-coding RNAs (lncRNAs) are emerging as key regulators in inflammation. However, their functions and profiles in LPS-induced inflammation in pi......

Lack of association between polymorphism of IL-2-330T/G and pulmonary tuberculosis among Caucasians

期刊: INNATE IMMUNITY, 2020; 26 (5)

This meta-analysis was conducted to assess the consistency and strength of the relationship between polymorphism of IL-2 -330T/G and susceptibility to......

Extracellular ATP is a potent signaling molecule in the activation of the Japanese flounder (Paralichthys olivaceus) innate immune responses

期刊: INNATE IMMUNITY, 2020; 26 (5)

Innate immunity is the first line of defense against pathogen infections. Extracellular ATP (eATP) is one of the most studied danger-associated molecu......

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