期刊： GENOME BIOLOGY, 2022; 23 (1)
Background The PRDM9-dependent histone methylation H3K4me3 and H3K36me3 function in assuring accurate homologous recombination at recombination hotspo......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background Salicaceae species have diverse sex determination systems and frequent sex chromosome turnovers. However, compared with poplars, the divers......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background Human endogenous retroviruses (HERVs), the remnants of ancient retroviruses, account for 8% of the human genome, but most have lost their t......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background: Garlic is an entirely sterile crop with important value as a vegetable, condiment, and medicine. However, the evolutionary history of garl......
期刊： GENOME BIOLOGY, 2022; 23 (1)
In this study, we propose iDNA-ABF, a multi-scale deep biological language learning model that enables the interpretable prediction of DNA methylation......
期刊： GENOME BIOLOGY, 2022; 23 (1)
BackgroundDespite having been extensively studied, it remains largely unclear why humans bear a particularly high risk of cancer. The antagonistic ple......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background Persian walnut, Juglans regia, occurs naturally from Greece to western China, while its closest relative, the iron walnut, Juglans sigillat......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Heat-imposed crop failure is often attributed to reduced thermotolerance of floral tissues; however, the underlying mechanism remains unknown. Here, w......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background: Cell-cell interactions are important for information exchange between different cells, which are the fundamental basis of many biological ......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background The daily cycling of plant physiological processes is speculated to arise from the coordinated rhythms of gene expression. However, the dyn......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Here, we present a multi-modal deep generative model, the single-cell Multi-View Profiler (scMVP), which is designed for handling sequencing data that......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Viruses change constantly during replication, leading to high intra-species diversity. Although many changes are neutral or deleterious, some can conf......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background Plant metabolites reshaped by nature and human beings are crucial for both their lives and human health. However, which metabolites respond......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Low efficiency has seriously restricted the application of prime editing (PE) systems in plants. In this study, we develop an enhanced plant prime edi......
期刊： GENOME BIOLOGY, 2022; 23 (1)
Background: Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular act......
