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Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2(V617F)-induced myeloproliferative neoplasms

期刊: BLOOD CANCER JOURNAL, 2022; 12 (3)

Janus kinase 2 (JAK2) hyperactivation by JAK2(V617F) mutation leads to myeloproliferative neoplasms (MPNs) and targeting JAK2 could serve as a promisi......

JIF:6.031

Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms

期刊: BLOOD CANCER JOURNAL, 2022; 12 (2)

Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these bio......

JIF:6.031

Next-day manufacture of a novel anti-CD19 CAR-T therapy for B-cell acute lymphoblastic leukemia: first-in-human clinical study

期刊: BLOOD CANCER JOURNAL, 2022; 12 (7)

To improve clinical outcomes and shorten the vein-to-vein time of chimeric antigen receptor T (CAR-T) cells, we developed the FasT CAR-T (F-CAR-T) nex......

JIF:6.031

An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial)

期刊: BLOOD CANCER JOURNAL, 2022; 12 (11)

The combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has been demonstrated to have comparable effectiveness or better to ATRA ......

JIF:6.031

CD19-targeted BiTE expression by an oncolytic vaccinia virus significantly augments therapeutic efficacy against B-cell lymphoma

期刊: BLOOD CANCER JOURNAL, 2022; 12 (2)

Immunotherapy with CD19-targeting bispecific T-cell engagers (CD19BiTEs) has demonstrated highly effective killing of cancer cells in patients with pr......

JIF:6.031

Novel CD19 chimeric antigen receptor T cells manufactured next-day for acute lymphoblastic leukemia

期刊: BLOOD CANCER JOURNAL, 2022; 12 (6)

Chimeric antigen receptor-engineered T (CAR-T) cells have shown promising efficacy in patients with relapsed/refractory B cell acute lymphoblastic leu......

JIF:6.031

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