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PGC-1: a key regulator in bone homeostasis

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (1)

Peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) is an inducible co-regulator of nuclear receptors and is involved in a wide var......

JIF:2.318

CircPVT1 promotes the tumorigenesis and metastasis of osteosarcoma via mediation of miR-26b-5p/CCNB1 axis

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (4)

Introduction Osteosarcoma (OS) is the most aggressive malignancy among the bone tumors in the world. Circular RNAs (circRNAs) have been reported to be......

JIF:2.318

CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF-kappa B pathway

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (5)

Introduction A genome-wide association analysis revealed a rheumatoid arthritis (RA)-risk-associated genetic locus on chromosome 9, which contained th......

JIF:2.318

The crosstalk between LINC01089 and hippo pathway inhibits osteosarcoma progression

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (6)

Introduction Osteosarcoma is the most common malignancy in children, with high morbidity worldwide. Researches indicated that long non-coding RNAs (ln......

JIF:2.318

Regulation of circADAMTS6-miR-324-5p-PIK3R3 ceRNA pathway may be a novel mechanism of IL-1 beta-induced osteoarthritic chondrocytes

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction A disintegrin and metallopeptidase with thrombospondin type 1 motif 6 (ADAMTS6)-derived circular RNA (circADAMTS6; hsa_circ_0008667) is a......

JIF:2.318

FSH may mediate the association between HbA1c and bone turnover markers in postmenopausal women with type 2 diabetes

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction Recent studies in postmenopausal women have found associations of follicle-stimulating hormone (FSH) levels with both glucose metabolism ......

JIF:2.318

Histone methyltransferase EZH2 in proliferation, invasion, and migration of fibroblast-like synoviocytes in rheumatoid arthritis

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (2)

Objective Rheumatoid arthritis (RA) may lead to irreversible joint damage. The role of histone modifications in RA has been emphasized. This study inv......

JIF:2.318

Emerging role of m6A modification in osteogenesis of stem cells

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (2)

The differentiation of stem cells into osteoblasts is a key link in the treatment of bone defects and other orthopedic diseases. N6-methyladenosine (m......

JIF:2.318

Hops extract and xanthohumol ameliorate bone loss induced by iron overload via activating Akt/GSK3 beta/Nrf2 pathway

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction Osteoporosis is closely related to iron metabolism. This study aimed to investigate whether hops extract (HLE) and its active component x......

JIF:2.318

Risk factors of mortality and second fracture after elderly hip fracture surgery in Shanghai, China

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (6)

Introduction Hip fracture is one of the leading causes of death and disability in the elderly. We analyzed the risk factors of mortality and second fr......

JIF:2.318

CircTMOD3 promotes lipopolysaccharide-induced chondrocyte apoptosis in osteoarthritis by sponging miR-27a

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction The progression of osteoarthritis (OA) requires the involvement of lipopolysaccharide (LPS)-induced inflammation, in which circTMOD3 play......

JIF:2.318

Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction To investigate the correlation between paraspinal muscles features and osteoporosis in lumbar spine. Materials and methods A total of 367......

JIF:2.318

Enamel matrix derivative expedites osteogenic differentiation of BMSCs via Wnt/beta-catenin pathway in high glucose microenvironment

期刊: JOURNAL OF BONE AND MINERAL METABOLISM, 2022; 40 (3)

Introduction The influence of enamel matrix derivative (EMD) on proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BM......

JIF:2.318

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