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LEAP2 has antagonized the ghrelin receptor GHSR1a since its emergence in ancient fish

期刊: AMINO ACIDS, 2021; 53 (6)

Recent studies have demonstrated that liver-expressed antimicrobial peptide 2 (LEAP2) antagonizes the ghrelin receptor GHSR1a in mammals. However, its......

The optimum dietary methionine requirement of juvenile humpback grouper (Cromileptes altivelis): effects on growth, micromorphology, protein and lipid metabolism

期刊: AMINO ACIDS, 2021; 53 (7)

An 8-week feeding trial was conducted to evaluate optimum dietary methionine (Met) requirement of juvenile humpback grouper (Cromileptes altivelis) an......

Disruption of kynurenine pathway reveals physiological importance of tryptophan catabolism in Henosepilachna vigintioctopunctata

期刊: AMINO ACIDS, 2021; 53 (7)

Kynurenine pathway is critically important to catabolize tryptophan, to produce eye chromes, and to protect nervous system in insects. However, severa......

Bioactive peptide apelin rescues acute kidney injury by protecting the function of renal tubular mitochondria

期刊: AMINO ACIDS, 2021; 53 (8)

Mitochondrial dysfunction in proximal tubular epithelial cells is a key event in acute kidney injury (AKI), which is a risk factor for the development......

Identification of a peptide that crosses the blood-cerebrospinal fluid barrier by phage display technology

期刊: AMINO ACIDS, 2021; 53 (8)

Treatments of brain diseases are heavily limited by the existence of the blood-brain barrier (BBB), which precludes efficient drug delivery to the bra......

Attenuation of doxorubicin-induced oxidative damage in rat brain by regulating amino acid homeostasis with Astragali Radix

期刊: AMINO ACIDS, 2021; 53 (6)

The nervous system disorders caused by doxorubicin (DOX) are among the severe adverse effects that dramatically reduce the quality of life of cancer s......

Alarin alleviated cardiac fibrosis via attenuating oxidative stress in heart failure rats

期刊: AMINO ACIDS, 2021; 53 (7)

The present study was to explore whether alarin could alleviate heart failure (HF) and attenuate cardia fibrosis via inhibiting oxidative stress. The ......

Promotion of rs3746804 (p. L267P) polymorphism to intracellular SLC52A3a trafficking and riboflavin transportation in esophageal cancer cells

期刊: AMINO ACIDS, 2021; 53 (8)

Riboflavin is an essential micronutrient for normal cellular growth and function. Lack of dietary riboflavin is associated with an increased risk for ......

Dietary L-arginine supplementation during days 14-25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts

期刊: AMINO ACIDS, 2021; 53 (8)

This study tested the hypothesis that dietary L-arginine (Arg) supplementation to pregnant gilts enhanced the expression of water channel proteins [aq......

Pellino1 deficiency reprograms cardiomyocytes energy metabolism in lipopolysaccharide-induced myocardial dysfunction

期刊: AMINO ACIDS, 2021; 53 (5)

Pellino1 has been shown to regulate proinflammatory genes by activating the nuclear factor kappa B (NF-kappa B) and Toll-like receptor (TLR) signaling......

Automatic radiosynthesis and preclinical evaluation of F-18-AlF-PSMA-NF as a potential PET probe for prostate cancer imaging

期刊: AMINO ACIDS, 2021; 53 (6)

Facile automatic production is important for the application of prostate-specific membrane antigen (PSMA) tracers in clinical practice. We developed a......

Association between dietary essential amino acids intake and metabolic biomarkers: influence of obesity among Chinese children and adolescents

期刊: AMINO ACIDS, 2021; 53 (5)

Essential amino acids (EAAs) are involved in growth and development in children and adolescents. This study was aimed at exploring the relationship be......

Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients

期刊: AMINO ACIDS, ; ()

Diabetic nephropathy (DN) is one of the major complications of diabetes and contributes significantly towards end-stage renal disease. Previous studie......

Host defense peptide LL-37 is involved in the regulation of cell proliferation and production of pro-inflammatory cytokines in hepatocellular carcinoma cells

期刊: AMINO ACIDS, ; ()

Recent studies on the roles and mechanisms of LL-37 have demonstrated that LL-37 can either serve as a tumor promoter or a tumor suppressor in differe......

Angiotensin-(1-7) attenuates collagen-induced arthritis via inhibiting oxidative stress in rats

期刊: AMINO ACIDS, 2021; 53 (2)

The present study was designed to investigate the anti-rheumatic effects and the mechanism of angiotensin (Ang)-(1-7) in rat models with collagen-indu......

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