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The N93D mutation of the human T-cell leukemia virus type 1 envelope glycoprotein found in symptomatic patients enhances neuropilin-1 b1 domain binding

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (11)

Human T-cell leukemia virus type 1 (HTLV-1) infection of host cells is mainly mediated by interactions with the viral envelope glycoprotein surface un......

Crystal structure of a chitinase (RmChiA) from the thermophilic fungus Rhizomucor miehei with a real active site tunnel

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (11)

A chitinase gene (RmChiA) encoding 445 amino acid (aa) residues from a fungus Rhizomucor miehei was cloned and overexpressed in Escherichia coli. Two ......

Proteomic insights into protostane triterpene biosynthesis regulatory mechanism after MeJA treatment in Alisma orientale (Sam.) Juz

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (8)

Protostane triterpenes in Alisma orientale (Sam.) Juz. have unique structural features with distinct pharmacological activities. Previously we have de......

Computational prediction and analysis of histone H3k27me1-associated miRNAs

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (1)

The mono-methylation of histone H3 on lysine 27 (H3K27me1) plays key roles in the cellular processes. The H3K27me1 interacts with the DNA sequence of ......

Mass spectrometry-based proteomics analyses of post-translational modifications and proteoforms in human pituitary adenomas

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (3)

Pituitary adenoma (PA) is a common intracranial neoplasm, which affects the hypothalamus-pituitary-target organ axis systems, and is hazardous to huma......

Determining protein-protein functional associations by functional rules based on gene ontology and KEGG pathway

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2021; 1869 (6)

Protein-protein interactions (PPIs) describe the direct physical contact of two proteins that usually results in specific biological functions or regu......

Production, thermodynamic characterization, and fruit juice quality improvement characteristics of an Exo-polygalacturonase from Penicillium janczewskii

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (5)

Exo-polygalacturonase (Exo-PG), an extracellular pectinolytic enzyme with great potential in the food industry, was produced from Penicillium janczews......

Review and comparative analysis of machine learning-based phage virion protein identification methods

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (6)

Phage virion protein (PVP) identification plays key role in elucidating relationships between phages and hosts. Moreover, PVP identification can facil......

Deep learning based prediction of species-specific protein S-glutathionylation sites

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (7)

As a widespread and reversible post-translational modification of proteins, S-glutathionylation specifically generates the mixed disulfides between cy......

A comprehensive study of construction and analysis of competitive endogenous RNA networks in lung adenocarcinoma

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (8)

Background: Long noncoding RNAs (lncRNAs) have gain increasing attention in lung adenocarcinoma. In this study, we aimed at constructing and analyzing......

Predicting protein subcellular location with network embedding and enrichment features

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (10)

The subcellular location of a protein is highly related to its function. Identifying the location of a given protein is an essential step for investig......

Insights into predicting diabetic nephropathy using urinary biomarkers

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (10)

Diabetic nephropathy (DN) is a serious complication of diabetes caused by changes in the structure and function of the kidneys. It is important to det......

Tetramer protein complex interface residue pairs prediction with LSTM combined with graph representations

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (11)

Motivation: Protein-protein interactions are important for many biological processes. Theoretical understanding of the structurally determining factor......

Decipher the connections between proteins and phenotypes

期刊: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2020; 1868 (11)

As the outward-most representation of life, phenotype is the fundamental basis with which humans understand life and disease. But with the advent of m......

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