期刊： TRENDS IN MOLECULAR MEDICINE, 2021; 27 (7)
Host-microbiota interactions are vital for diverse pathophysiological events and may be targeted for innovative therapeutics. Nuclear receptors (NRs) ......
期刊： TRENDS IN MOLECULAR MEDICINE, 2021; 27 (3)
Immune checkpoints negatively regulate immune cell responses. Programmed cell death protein 1:programmed death ligand 1 (PD-1:PD-L1) and cytotoxic T l......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (1)
Mitochondria have emerged as key contributors to the organismal homeostasis, in which mitochondrial regulation of stem cells is becoming increasingly ......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (2)
Spermatogenesis is supported by intricate crosstalk between Sertoli cells and germ cells including spermatogonia, spermatocytes, haploid spermatids, a......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (2)
Nuclear factor erythroid 2-related factor 2 (Nrf2) is ubiquitously expressed in most eukaryotic cells and functions to induce a broad range of defense......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (5)
The recent outbreak of COVID-19 in Wuhan turned into a public health emergency of international concern. With no antiviral drugs nor vaccines, and the......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (5)
Near-IR fluorescence imaging (NIRFI) is a highly promising technique for improving cancer theranostics in the era of precision medicine. Through the c......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (5)
Obesity is known to increase breast cancer incidence and mortality, but the underlying mechanisms remain unsolved. Recent studies demonstrate that adi......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (6)
Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) represent two major health burdens with steadily increasing prevalence and accumulating e......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (12)
As the major feature of pancreatic ductal adenocarcinoma (PDAC), desmoplastic stroma poses a significant obstacle for treatment. Recent studies reveal......
期刊： TRENDS IN MOLECULAR MEDICINE, 2020; 26 (9)
The pathogenesis of autoimmune diseases (AIDs) is not only attributed to genetic susceptibilities but also environmental factors, among which, disturb......
期刊： TRENDS IN MOLECULAR MEDICINE, 2019; 25 (8)
miRNA is a class of short noncoding RNA that regulates gene expression at the post-transcriptional level. Evidence of age-associated changes in miRNA ......
期刊： TRENDS IN MOLECULAR MEDICINE, 2019; 25 (9)
Type 1 (T1D) and type 2 diabetes (T2D), two distinct clinical entities principally driven by autoimmunity and metabolic dysfunction, respectively, are......
