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A randomized controlled trial to evaluate omentum-preserving gastrectomy for patients with T1-T3 gastric cancer

期刊: FUTURE ONCOLOGY, 2021; 17 (25)

Although complete omentectomy is traditionally performed in patients with gastric cancer as part of radical gastrectomy to ensure the elimination of m......

Preclinical activity of cobimetinib alone or in combination with chemotherapy and targeted therapies in renal cell carcinoma

期刊: FUTURE ONCOLOGY, 2021; 17 (23)

Background: The poor outcome of advanced renal cell carcinoma (RCC) necessitates new treatments. Cobimetinib is a MEK inhibitor and approved for the t......

Clinical utility of the systemic immune-inflammation index for predicting survival in esophageal squamous cell carcinoma after radical radiotherapy

期刊: FUTURE ONCOLOGY, 2021; 17 (20)

Aim: To explore the clinical utility of the systemic immune-inflammation index (SII) for predicting the prognosis of esophageal squamous cell carcinom......

Indications for and contraindications of immune checkpoint inhibitors in cancer patients with coronavirus disease 2019 vaccination

期刊: FUTURE ONCOLOGY, 2021; 17 (26)

The novel coronavirus disease 2019 (COVID-19) pandemic has lasted over 1 year and will not disappear in a short time. There is no specific remedy agai......

Laboratory indicators predict axillary nodal pathologic complete response after neoadjuvant therapy in breast cancer

期刊: FUTURE ONCOLOGY, 2021; 17 (19)

Lay abstract The purpose of this study was to integrate more pretreatment indicators, including clinicopathological factors and simple laboratory indi......

RAB1A regulates glioma cellular proliferation and invasion via the mTOR signaling pathway and epithelial-mesenchymal transition

期刊: FUTURE ONCOLOGY, 2021; 17 (24)

Aim: We aimed at investigating the mechanism of RAB1A proliferation and invasion in gliomas. Materials & methods: Genome-wide expression profile d......

Upregulated expression of MTFR2 as a novel biomarker predicts poor prognosis in hepatocellular carcinoma by bioinformatics analysis

期刊: FUTURE ONCOLOGY, 2021; 17 (24)

Aim: The authors investigated the clinical role of MTFR2 in hepatocellular carcinoma (HCC) progression. Results: MTFR2 expression and methylation were......

Expression profiles and prognostic roles of m6A writers, erasers and readers in gastric cancer

期刊: FUTURE ONCOLOGY, 2021; 17 (20)

Aim: To explore the expression profiles of N6-methyladenosine (m6A) enzymes (writers, erasers and readers) and their associations with gastric cancer ......

Current and potential biomarkers in gastric cancer: a critical review of the literature

期刊: FUTURE ONCOLOGY, 2021; 17 (25)

Lay abstract Gastric cancer is the fourth most common type of cancer worldwide and the second most lethal. Gastric cancer biomarkers are molecules tha......

NAT1 is a critical prognostic biomarker and inhibits proliferation of colorectal cancer through modulation of PI3K/Akt/mTOR

期刊: FUTURE ONCOLOGY, 2021; 17 (19)

Lay abstract Colorectal cancer (CRC) is a common malignancy worldwide. Because of the limited understanding of the pathogenesis and prognostic factors......

Global evolution of research on pulmonary nodules: a bibliometric analysis

期刊: FUTURE ONCOLOGY, 2021; 17 (20)

Aim: To provide a historical and global picture of research concerning lung nodules, compare the contributions of major countries and explore research......

Immune-related genes LAMA2 and IL1R1 correlate with tumor sites and predict poor survival in pancreatic adenocarcinoma

期刊: FUTURE ONCOLOGY, 2021; 17 (23)

Lay abstract The prognosis of pancreatic cancer is poor, and pancreatic head carcinoma is different from pancreatic body/tail carcinoma in many respec......

Nomograms for predicting cancer-specific and overall survival in patients with invasive extramammary Paget's disease

期刊: FUTURE ONCOLOGY, 2021; 17 (21)

Aim: To develop nomograms for predicting cancer-specific survival (CSS) and overall survival (OS) in patients with invasive extramammary Paget's disea......

High PD-L1 expression on immune cells, but not on tumor cells, is a favorable prognostic factor in urothelial carcinoma

期刊: FUTURE ONCOLOGY, 2021; 17 (22)

Aims: To explore the prognostic value of high PD-L1 expression on tumor cells (TC) and tumor-infiltrating immune cells (TIIC) in urothelial carcinoma ......

Identification of a lncRNA prognostic signature-related to stem cell index and its significance in colorectal cancer

期刊: FUTURE ONCOLOGY, 2021; 17 (23)

Background: The relationship between long noncoding RNAs (lncRNAs) and the mRNA stemness index (mRNAsi) in colorectal cancer (CRC) is still unclear. M......

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