期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (21)
As an important post-transcription modification, histone deacetylation plays significant roles in chromatin remodeling and gene expression. The aberra......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (5)
Coronary heart disease (CHD) is closely related to hypercholesterolemia, and lowering serum cholesterol is currently the most important strategy in re......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (9)
Background: Chronic consumption of alcohol has an adverse effect on the skeletal system, which may lead to osteoporosis, delayed fracture healing and ......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (5)
DNA damage response (DDR) is a complicated interactional pathway. Defects that occur in subordinate pathways of the DDR pathway can lead to genomic in......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (21)
Sigma-2 receptor plays key roles in promoting tumor cell apoptosis, enhancing efficacy of anti-tumor drugs, blocking signal transduction controlled by......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (18)
Atherosclerosis is a chronic arterial wall illness that forms atherosclerotic plaques within the arteries. Plaque formation and endothelial dysfunctio......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (14)
Tanshinones are an important type of natural products isolated from Salvia miltiorrhiza Bunge with various bioactivities. Tanshinone IIa, cryptotanshi......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (5)
Flavonoids, commonly found in various plants, are a class of polyphenolic compounds having a basic structural unit of 2-phenylchromone. Flavonoid comp......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (24)
HIV-1 integrase catalyzed the insertion of viral DNA into the genome of human cells in the process of retrotranscription. Integrase is an attractive t......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (13)
Tumor growth inhibition can be achieved by inhibiting angiogenesis, which has been a field of great concern in recent years. Important targets to inhi......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (18)
Kidney disease is a serious health problem that burdens our healthcare system. It is crucial to find the accurate pathogenesis of various types of kid......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (6)
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a local or systemic inflammatory response. At present, the in......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (7)
PROTAC (Proteolysis Targeting Chimera) degraders based on protein knockdown technology are now suggested as a novel option for the treatment of variou......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (25)
Objective and Aims: This study aims to conduct a systematic review and meta-analysis for prospective studies to investigate the improvement effects of......
期刊： CURRENT MEDICINAL CHEMISTRY, 2021; 28 (18)
COX-2, a key enzyme that catalyzed the rate-limiting steps in the conversion of arachidonic acid to prostaglandins, played a pivotal role in the infla......
