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Screening and identification of key genes in EBV-associated gastric carcinoma based on bioinformatics analysis

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 222 ()

Epstein-Barr virus (EBV) infection is closely related to gastric carcinoma (GC). In this study, we identified a set of DEGs (different expression gene......

SRp20: A potential therapeutic target for human tumors

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

As an important member of SR protein family, SRp20 plays a crucial role in alternative splicing. It not only participates in cell cycle regulation, ex......

The novel target of esophageal squamous cell carcinoma: lncRNA GASL1 regulates cell migration, invasion and cell cycle stagnation by inactivating the Wnt3a/ll-catenin signaling

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 217 ()

Long non-coding RNA (lncRNA) Growth-Arrest Associated LncRNA 1 (GASL1) is a lncRNA with a suppressive role in glioma, prostate carcinoma and gastric c......

Circ_0084615 is an oncogenic circular RNA in colorectal cancer and promotes DNMT3A expression via repressing miR-599

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

Background: Circular RNAs (circRNAs) are implicated in modulating cancer progression, exerting a pro- or anticancer effect. This work is aimed to prob......

Methylation status of ADAM12 promoter are associated with its expression levels in colorectal cancer

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 221 ()

Background: Colorectal cancer (CRC) is a kind of malignant tumor of digestive system severely affecting human health. The occurrence of CRC is a polyg......

Sorafenib blocks the activation of the HIF-2?/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 220 ()

Background: Insufficient high-intensity focused ultrasound (HIFU) can promote the rapid progression of the residual tumor through the hypoxia inducibl......

LncRNA-HCG18 regulates the viability, apoptosis, migration, invasion and epithelial-mesenchymal transition of papillary thyroid cancer cells via regulating the miR-106a-5p/PPP2R2A axis

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 221 ()

The incidence of papillary thyroid cancer (PTC) has experienced a rapid increase in recent years. Long noncoding RNA-homo sapiens HLA complex group (H......

MiR-135a-5p inhibits vascular smooth muscle cells proliferation and migration by inactivating FOXO1 and JAK2 signaling pathway

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

Background: It is reportedly demonstrated that miR-135a-5p plays a critical role in cancer cells, macrophages, and endothelia cells. However, little i......

miR-133b inhibits cell proliferation, migration, and invasion of lung adenocarcinoma by targeting CDCA8

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 223 ()

Objective: Lung adenocarcinoma (LUAD) is the most common type of lung cancer. This study aims to explore the mechanism by which CDCA8 regulates cell p......

Long noncoding RNA ANCR promotes migration, invasion, EMT progress and stemness of nasopharyngeal carcinoma cells via the miR-4731-5p/ NMT1 axis

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

Background: In our previous study, we revealed that Antidifferentiation noncoding RNA (ANCR) promoted proliferation and radiation resistance of nasoph......

Decreased infiltration of CD4(+) Th1 cells indicates a good response to ursodeoxycholic acid (UDCA) in primary biliary cholangitis

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 217 ()

Background: Primary biliary cholangitis (PBC) is characterized by nonsuppurative destructive cholangitis and is thought to be an autoimmune disorder. ......

Mutant CDKN2A regulates P16/p14 expression by alternative splicing in renal cell carcinoma metastasis

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 223 ()

Objective: Metastatic renal cell carcinoma (mRCC) is the important factor for patient mortality, meanwhile gene mutation constantly changes cancer pro......

MUC1 regulates AKT signaling pathway by upregulating EGFR expression in ovarian cancer cells

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

MUC1, a type I transmembrane glycoprotein, mediates tumor growth and cellular differentiation in various types of cancers. However, the mechanism of M......

A positive feedback loop of LINC00662 and STAT3 promotes malignant phenotype of glioma

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2021; 224 ()

Background: Long noncoding RNAs (lncRNAs) have been reported to be associated with tumorigenesis and development of glioma. LINC00662 has been involve......

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