Chronic constriction injury (CCI) of the sciatic nerve was used to establish neuropathic pain (NP) models in rats. CCI rats were then treated with pro......
Traumatic brain injury (TBI) is a world-wide leading health problem with high morbidity and mortality rates. Emerging studies have demonstrated that T......
期刊： SYNAPSE, ; ()
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are a special type of ganglion cell that express the photopigment melanopsin and autonomo......
Alzheimer's disease (AD) is the leading cause of dementia and is incurable. The widely accepted amyloid hypothesis failed to produce efficient clinica......
Post-traumatic stress disorder (PTSD) is a long-lasting mental disorder and accompanied by worse fear extinction. Enhanced fear memory or poor fear ex......
Increasing evidence suggests that changes in the triggering receptor expressed on myeloid cells 2 (TREM2) is closely correlated with the pathological ......
Inflammation and oxidative stress play a key role in mediating the pathophysiology of hypoxic-ischemic (HI) brain injury. Nrf2 is a transcriptional fa......
Microglia, the resident immune cells of the central nervous system, play critical roles in neurodevelopment, synaptic pruning, and neuronal wiring. Ea......
期刊： SYNAPSE, 0; ()
We aimed to compare the performance of acellular nerves prepared by different decellularization methods, screening out the optimal decellularization p......
Peripheral nerve gaps often lead to interrupted innervation, manifesting as severe sensory and motor dysfunctions. The repairs of the nerve injuries h......
Neuropathic pain is caused by somatosensory nervous system disorder which happens in patients with different diseases. Akt3 regulates innate immune fu......
期刊： SYNAPSE, 0; ()
Synapse impairment is associated with post-traumatic stress disorder (PTSD), which is characterized by enhanced apoptosis in the hippocampus, amygdala......
Transient receptor melastatin 2 (TRPM2) is a nonselective Ca2+-permeable cation channel highly expressed in brain and other tissues. Studies showed th......
PurposeLamotrigine (LTG) is a broad-spectrum antiepileptic drug that is widely used in clinic. However, the effect of LTG on cognition and neurodegene......
Purpose: Smad anchor for receptor activation (SARA) is an important regulator of transforming growth factor beta (TGF-beta) signaling by recruiting Sm......
