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Prediction of lymph node metastasis in oral tongue squamous cell carcinoma using the neutrophil-to-lymphocyte ratio and platelet-to-neutrophil ratio

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (6)

Background Lymph node metastasis in a variety of tumors is associated with systemic inflammatory markers. However, this association has not been repor......

EQA/PT scheme to improve the equivalence of enzymatic results between mutual recognition laboratories in Beijing

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (6)

Background To utilize the external quality assessment (EQA)/proficiency testing (PT) scheme to evaluate the equivalence of different clinical enzymati......

Nonradioactive direct telomerase activity detection using biotin-labeled primers

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (6)

Background Telomerase is a ribonucleoprotein enzyme responsible for maintenance of telomere length which expressed in more than 85% of cancer cells bu......

The clinical significance of spondin 2 eccentric expression in peripheral blood mononuclear cells in bronchial asthma

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (6)

Background Bronchial asthma (BA) was a heterogeneous disease characterized by chronic airway inflammation. Spondin 2 (SPON2) was reported to be implic......

Evaluating the accuracy and diagnostic value of CFW and a new fluorescent reagents, fluorescent brightener 85, for the diagnosis of vulvovaginal candidiasis

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (8)

Background Vulvovaginal candidiasis (VVC) is a common vaginitis in females. The commonly used diagnostic method, 10% potassium hydroxide (KOH) smear m......

CircRNAs as promising biomarker in diagnosis of breast cancer: An updated meta-analysis

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (9)

Background Circular RNAs (circRNAs) have been identified to be involved in onset and progression of multiple malignant tumors. The present study aimed......

Hsa_circ_0031787 promotes cell proliferation and invasion in colorectal cancer

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (7)

Objective: Circular RNA (circRNA) has been found to be involved in regulating tumor development. However, the roles and underlying mechanisms of circR......

MiR-221-3p and miR-92a-3p enhances smoking-induced inflammation in COPD

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (7)

Background Smoking is likely to facilitate airway inflammation and finally contributes to chronic obstructive pulmonary disease (COPD). This investiga......

Application of high-throughput sequencing for hereditary thrombocytopenia in southwestern China

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (8)

Background The aim of this study was to design and analyze the applicability of a 21-gene high-throughput sequencing (HTS) panel in the molecular diag......

Immunological characteristics and effect of cyclosporin in patients with immune thrombocytopenia

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (9)

Objective Immune thrombocytopenia (ITP) is well-known as an antibody-mediated autoimmune disease, and it is easy to get response but often turns to re......

Performance of noninvasive tools for identification of minimal liver fibrosis in patients with hepatitis B virus infection

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (9)

Background Various noninvasive liver fibrosis assessment tools are available. Here, we evaluated the performance of the asparagine aminotransferase-to......

A combination of ssGSEA and mass cytometry identifies immune microenvironment in muscle-invasive bladder cancer

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (5)

Background Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease with varying clinical courses and responses to treatment. To improve the p......

Association between preoperative lipid profiles and new-onset diabetes after transplantation in Chinese kidney transplant recipients: A retrospective cohort study

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (8)

Background This study investigated the association between the preoperative lipid profiles and new-onset diabetes after transplantation (NODAT) in Chi......

Clinical value of INSL3 in the diagnosis and development of diabetic nephropathy

期刊: JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2021; 35 (9)

Background Insulin-like factor 3 (INSL3) was stated to be an essential regulator in many diseases. This present study aimed to explore the underlying ......

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