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FOXI1 inhibits gastric cancer cell proliferation by activating miR-590/ATF3 axis via integrating ChIP-seq and RNA-seq data

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2021; 163 ()

FOXI1 plays a key role in the development of gastric cancer. However, the whole genome FOXI1 binding sites and its target genes are unclear. In the pr......

A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2021; 160 ()

Mammalian cells contain an elaborate network of organelles and molecular machines that orchestrate essential cellular processes. Visualization of this......

Reprint of "Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation"

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2021; 160 ()

Cryo-electron microscopy (cryoEM) has become one of the most important approach for structural biology. However, barriers are still there for an incre......

A quantitative approach relating emergent features of complex traits to protein expression

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2021; 161 ()

Linking complex, multigenic traits to protein activity is an important challenge in current biology, including applications in the medical sciences, a......

Ferroptosis as an emerging target in inflammatory diseases

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2020; 155 ()

Cell survival or death is one critical issue in inflammatory responses. Ferroptosis, which is characterized by iron-dependent lethal lipid peroxidatio......

Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2020; 156 ()

Cryo-electron microscopy (cryoEM) has become one of the most important approach for structural biology. However, barriers are still there for an incre......

Comprehensive analysis of the codon usage patterns of polyprotein of Zika virus

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2020; 150 ()

Zika virus (ZIKV) is a mosquito-borne virus in the family Flaviviridae, and the massive outbreak of ZIKV has endangered public health. Codon usage pat......

Recent treatment progress of triple negative breast cancer

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2020; 151 ()

Breast cancer (BC) is a serious worldwide disease that threatens women's health. Particularly, the morbidity of triple-negative breast cancer (TNBC) i......

Non-coding RNAs regulate autophagy process via influencing the expression of associated protein

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2020; 151 ()

Autophagy is a tightly-regulated multi-step process involving the lysosomal degradation of proteins and cytoplasmic organelles. Central to this proces......

Advances in mechanism studies on ultrasonic gene delivery at cellular level

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 142 ()

Ultrasound provides a means for intracellular gene delivery, contributing to a noninvasive and spatiotemporally controllable strategy suitable for cli......

JIF:2.7

Structurally- and dynamically-driven allostery of the chymotrypsin-like proteases of SARS, Dengue and Zika viruses

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 143 ()

Coronavirus 3C-like and Flavivirus NS2B-NS3 proteases utilize the chymotrypsin fold to harbor their catalytic machineries but also contain additional ......

JIF:2.7

Uncovering metastability and disassembly hotspots in whole viral particles

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 143 ()

Viruses are metastable macromolecular assemblies that toggle between multiple conformational states through molecular rearrangements that are critical......

JIF:2.7

MiR-132 promotes the proliferation, invasion and migration of human pancreatic carcinoma by inhibition of the tumor suppressor gene PTEN

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 149 ()

MicroRNA (miRNAs) emerges as key oncogene or tumor suppressor in a variety of cancers including pancreatic carcinoma. In this study, we detected the r......

JIF:2.7

Hypotonicity promotes epithelial gap closure by lamellipodial protrusion

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 149 ()

The closure of gaps within epithelia is an essential part of many physiological and pathological processes, such as embryonic development, organ remod......

JIF:2.7

Mechanical microenvironment regulation of age-related diseases involving degeneration of human skeletal and cardiovascular systems

期刊: PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2019; 149 ()

Age-related diseases involving degeneration of human skeletal and cardiovascular systems are now critical problems worldwide. The current review focus......

JIF:2.7

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