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Coinfection of porcine deltacoronavirus and porcine epidemic diarrhea virus altered viral tropism in gastrointestinal tract in a piglet model

期刊: VIROLOGY, 2021; 558 ()

Coinfection of porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV) is one of common findings in diarrheal piglets that cause m......

SARS_CoV2 RBD gene transcription cannot be driven by CMV promoter

期刊: VIROLOGY, 2021; 558 ()

Cytomegalovirus (CMV) promoter drives various gene expression and yields sufficient protein for further functional investigation. Receptor binding dom......

Influenza A virus NS1 induces degradation of sphingosine 1-phosphate lyase to obstruct the host innate immune response

期刊: VIROLOGY, 2021; 558 ()

The type I interferon (IFN)-mediated innate immune response is one of the central obstacles influenza A virus (IAV) must overcome in order to successf......

CD4(+) T cell depletion does not affect the level of viremia in chronically SHIVSF162P3N-infected Chinese cynomolgus monkeys

期刊: VIROLOGY, 2021; 560 ()

Chronically SHIVSF162P3N-infected cynomolgus monkeys were used to determine the effects of the antibodymediated acute CD4(+) T cell depletion on viral......

Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2

期刊: VIROLOGY, 2021; 560 ()

A recent study have reported that pre-use of azelastine is associated with a decrease in COVID-19 positive test results among susceptible elderly peop......

Gene expression patterns of Cydia pomonella granulovirus in codling moth larvae revealed by RNAseq analysis

期刊: VIROLOGY, 2021; 558 ()

The Cydia pomonella granulovirus (CpGV) has been used as a biological control agent of codling moth (Cydia pomonella), a severe global pest on pome fr......

Immunization with a recombinant fusion of porcine reproductive and respiratory syndrome virus modified GP5 and ferritin elicits enhanced protective immunity in pigs

期刊: VIROLOGY, 2021; 552 ()

Porcine reproductive and respiratory syndrome (PRRS) has caused huge economic losses in the swine industry worldwide. Live and inactivated vaccines ha......

Bombyx mori nucleopolyhedrovirus F-like protein Bm14 is a factor for viral-induced cytopathic effects via regulating oxidative phosphorylation and cellular ROS levels

期刊: VIROLOGY, 2021; 552 ()

Bombyx mori nucleopolyhedrovirus (BmNPV) is highly pathogenic to Bombyx mori, silkworm, which causes serious cytopathic effects (CPEs) during infectio......

Generation and preliminary characterization of vertebrate-specific replication-defective Zika virus

期刊: VIROLOGY, 2021; 552 ()

Zika virus (ZIKV) is a mosquito-borne flavivirus that replicates in both vertebrate and insect cells, whereas insect -specific flaviviruses (ISF) repl......

Effect of SARS-CoV-2 coinfection was not apparent on the dynamics of chronic hepatitis B infection

期刊: VIROLOGY, 2021; 553 ()

In patients coinfected with SARS-CoV-2 and HBV, liver injury was common. However, the interactions between SARS-CoV-2 and HBV coinfection remained unk......

Characterization of a novel genomovirus in the phytopathogenic fungus Botrytis cinerea

期刊: VIROLOGY, 2021; 553 ()

This study characterized a single-stranded circular DNA virus in Botrytis cinerea-namely, Botrytis cinerea genomovirus 1 (BcGV1). The genome of BcGV1 ......

Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5

期刊: VIROLOGY, 2021; 553 ()

Many viruses utilize molecular chaperone heat shock protein 90 (Hsp90) for protein folding and stabilization, however, the role of Hsp90 in herpesviru......

Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants

期刊: VIROLOGY, 2021; 553 ()

Increasing evidences indicate that high-risk HPV variants are heterogeneous in carcinogenicity and ethnic dispersion. In this work, we identified gene......

Dexamethasone inhibits SARS-CoV-2 spike pseudotyped virus viropexis by binding to ACE2

期刊: VIROLOGY, 2021; 554 ()

The SARS-CoV-2 outbreak, began in late 2019, has caused a worldwide pandemic and shows no signs of slowing. Glucocorticoids (GCs), including dexametha......

The phylogeographic history of tomato mosaic virus in Eurasia

期刊: VIROLOGY, 2021; 554 ()

Tomato mosaic virus (ToMV) is a tobamovirus affecting solanaceous crops worldwide. The process of its emergence, however, is poorly understood. Here, ......

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