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Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production

期刊: CELLULAR SIGNALLING, 2022; 98 ()

Intraplaque hemorrhage (IPH) accelerates atherosclerosis progression. To scavenge excessive red blood cells (RBCs), vascular smooth muscle cells (VSMC......

JIF:4.132

CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer

期刊: CELLULAR SIGNALLING, 2022; 100 ()

Chromodomain helicase DNA binding protein 4 (CHD4), as a core component of the nucleosome remodeling and deactetylase (NuRD) complex, participated in ......

JIF:4.132

Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats

期刊: CELLULAR SIGNALLING, 2022; 89 ()

Ror2 plays an important role in neuronal development, neuronal plasticity, and neuropathic pain. In our previous pilot study, we found that Ror2 and G......

JIF:4.132

Glioma cell-derived FGF20 suppresses macrophage function by activating beta-catenin

期刊: CELLULAR SIGNALLING, 2022; 89 ()

Macrophages, which are the main regulators of the tumor-associated microenvironment, play a crucial role in the progression of various tumors. The ant......

JIF:4.132

CRISPR/Cas9-mediated knockout of SGLT1 inhibits proliferation and alters metabolism of gastric cancer cells

期刊: CELLULAR SIGNALLING, 2022; 90 ()

Background: The roles played by sodium/glucose cotransporters 1 (SGLT1) that transport glucose in cells independent of extracellular glucose concentra......

JIF:4.132

HOXD9 transcriptionally induced UXT facilitate breast cancer progression via epigenetic modification of RND3

期刊: CELLULAR SIGNALLING, 2022; 90 ()

Background: Ubiquitously expressed transcript (UXT) is a prefoldin-like protein. It was reported that UXT played vital role in several cancer types. H......

JIF:4.132

MiR-155 regulates m(6)A level and cell progression by targeting FTO in clear cell renal cell carcinoma

期刊: CELLULAR SIGNALLING, 2022; 91 ()

Although FTO, as an eraser of N6-methyladenosine (m(6)A), plays context-dependent tumor-suppressive and oncogenic roles in various cancer type, underl......

JIF:4.132

EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2? expression in diabetic nephropathy

期刊: CELLULAR SIGNALLING, 2022; 98 ()

Renal tubular damage occurs early in diabetic nephropathy (DN) and may play a key role in the progression of kidney disease. E1A binding protein P300 ......

JIF:4.132

GLI3 and androgen receptor are mutually dependent for their malignancy-promoting activity in ovarian and breast cancer cells

期刊: CELLULAR SIGNALLING, 2022; 92 ()

Hedgehog signaling pathway has been previously elucidated to be inappropriately activated in many human cancers, including ovarian and breast cancer. ......

JIF:4.132

Dynamic regulation of O-GlcNAcylation and phosphorylation on STAT3 under hypoxia-induced EMT

期刊: CELLULAR SIGNALLING, 2022; 93 ()

Activation of signal transducer and activator of transcription 3 (STAT3) is associated with hypoxia-induced epithelial-mesenchymal transition (EMT). A......

JIF:4.132

GPx8 regulates apoptosis and autophagy in esophageal squamous cell carcinoma through the IRE1/JNK pathway

期刊: CELLULAR SIGNALLING, 2022; 93 ()

Glutathione peroxidase 8 (GPx8) belongs to a family of enzymes that have a critical role in controlling levels of reactive oxygen species (ROS). GPX f......

JIF:4.132

KIAA1522 is a new biomarker of promoting the tumorigenesis and distant metastasis of colorectal carcinoma

期刊: CELLULAR SIGNALLING, 2022; 90 ()

Purpose: Our research was absorbed into exploring the expression, clinicopathological value, biological signifi-cance and signaling pathway of KIAA152......

JIF:4.132

Regulation of the unfolded protein response transducer IRE1? by SERPINH1 aggravates periodontitis with diabetes mellitus via prolonged ER stress

期刊: CELLULAR SIGNALLING, 2022; 91 ()

The hyperglycemic microenvironment induced by diabetes mellitus aggravates the inflammatory response, in which the IRE1 alpha signal transduction path......

JIF:4.132

LncRNA RP11-214F16.8 drives breast cancer tumorigenesis via a post-translational repression on NISCH expression

期刊: CELLULAR SIGNALLING, 2022; 92 ()

Increasing research interests have been aroused in exploring the function of long non-coding RNA (lncRNA) in breast cancer and developing lncRNA-targe......

JIF:4.132

Quercetin attenuates sepsis-induced acute lung injury via suppressing oxidative stress-mediated ER stress through activation of SIRT1/AMPK pathways

期刊: CELLULAR SIGNALLING, 2022; 96 ()

Endoplasmic reticulum (ER) stress and mitochondrial dysfunction play a pivotal role in the pathological process of sepsis-induced acute lung injury (A......

JIF:4.132

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