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Exploration of the regulatory relationship between KRAB-Zfp clusters and their target transposable elements via a gene editing strategy at the cluster specific linker-associated sequences by CRISPR-Cas9

期刊: MOBILE DNA, 2022; 13 (1)

Background Kruppel Associated Box-containing Zinc Finger Proteins (KRAB-ZFPs), representing the largest superfamily of transcription factors in mammal......

JIF:3.837

RNA sensor MDA5 suppresses LINE-1 retrotransposition by regulating the promoter activity of LINE-1 5 '-UTR

期刊: MOBILE DNA, 2022; 13 (1)

Background: Type 1 long interspersed elements, or LINE-1, are the only retroelements that replicate autonomously in human cells. The retrotranspositio......

JIF:3.837

A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1

期刊: MOBILE DNA, 2021; 12 (1)

Background Toll-like receptors (TLRs) play important roles in building innate immune and inducing adaptive immune responses. Associations of the TLR g......

SINE jumping contributes to large-scale polymorphisms in the pig genomes

期刊: MOBILE DNA, 2021; 12 (1)

Background Molecular markers based on retrotransposon insertion polymorphisms (RIPs) have been developed and are widely used in plants and animals. Sh......

The IS6 family, a clinically important group of insertion sequences including IS26

期刊: MOBILE DNA, 2021; 12 (1)

The IS6 family of bacterial and archaeal insertion sequences, first identified in the early 1980s, has proved to be instrumental in the rearrangement ......

Evolution of pogo, a separate superfamily of IS630-Tc1-mariner transposons, revealing recurrent domestication events in vertebrates

期刊: MOBILE DNA, 2020; 11 (1)

Background Tc1/marinerandZator, as two superfamilies ofIS630-Tc1-mariner(ITm) group, have been well-defined. However, the molecular evolution and dome......

Intruder (DD38E), a recently evolved sibling family of DD34E/Tc1 transposons in animals

期刊: MOBILE DNA, 2020; 11 (1)

Background A family of Tc1/mariner transposons with a characteristic DD38E triad of catalytic amino acid residues, named Intruder (IT), was previously......

SINE Retrotransposon variation drives Ecotypic disparity in natural populations of Coilia nasus

期刊: MOBILE DNA, 2020; 11 (1)

Background SINEs are a type of nonautonomous retrotransposon that can transpose from one site to be integrated elsewhere in an organism genome. SINE i......

The landscape of transposable elements and satellite DNAs in the genome of a dioecious plant spinach (Spinacia oleracea L.)

期刊: MOBILE DNA, 2019; 10 ()

BackgroundRepetitive sequences, including transposable elements (TEs) and satellite DNAs, occupy a considerable portion of plant genomes. Analysis of ......

JIF:3.63

Incomer, a DD36E family of Tc1/mariner transposons newly discovered in animals

期刊: MOBILE DNA, 2019; 10 (1)

Background The Tc1/mariner superfamily might represent the most diverse and widely distributed group of DNA transposons. Several families have been id......

JIF:3.63

Retrotransposons evolution and impact on lncRNA and protein coding genes in pigs

期刊: MOBILE DNA, 2019; 10 ()

BackgroundRetrotransposons are the major determinants of genome sizes and they have shaped both genes and genomes in mammalian organisms, but their ov......

JIF:3.63

Characterization of a novel Helitron family in insect genomes: insights into classification, evolution and horizontal transfer

期刊: MOBILE DNA, 2019; 10 ()

Background: Helitrons play an important role in shaping eukaryotic genomes due to their ability to transfer horizontally between distantly related spe......

JIF:3.63

A mobile restriction modification system consisting of methylases on the IncA/C plasmid

期刊: MOBILE DNA, 2019; 10 ()

BackgroundIncA/C plasmids play important roles in the development and dissemination of multidrug resistance in bacteria. These plasmids carry three me......

JIF:3.63

Amplification of miniature inverted-repeat transposable elements and the associated impact on gene regulation and alternative splicing in mulberry (Morus notabilis)

期刊: MOBILE DNA, 2019; 10 ()

BackgroundMiniature inverted-repeat transposable elements (MITEs) are common in eukaryotic genomes, and are important for genomic evolution.ResultsIn ......

JIF:3.63

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