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The miR-302s/367 Cluster Inhibits the Proliferation and Apoptosis in Sheep Fetal Fibroblasts via the Cell Cycle and PI3K-Akt Pathways

期刊: MAMMALIAN GENOME, 2021; 32 (3)

The miR-302s/367 family has the ability to induce mouse and human somatic cell reprogramming into induced pluripotent stem cells (iPSCs), inhibit the ......

ALKBH5-mediated m6A demethylation of lncRNA RMRP plays an oncogenic role in lung adenocarcinoma

期刊: MAMMALIAN GENOME, 2021; 32 (3)

Lung adenocarcinomas are more common in non-smoking males and females. In this study, we investigated the function of long non-coding RNA RMRP in lung......

The regulation mechanisms and the Lamarckian inheritance property of DNA methylation in animals

期刊: MAMMALIAN GENOME, 2021; 32 (3)

DNA methylation is a stable and heritable epigenetic mechanism, of which the main functions are stabilizing the transcription of genes and promoting g......

Sequence and haplotypes of ankyrin 1 gene (ANK1) and their association with carcass and meat quality traits in yak

期刊: MAMMALIAN GENOME, 2021; 32 (2)

Ankyrin 1 (ANK1) gene has been demonstrated to be a functional candidate gene for meat quality that helps to constitute and maintain the structure of ......

Novel mutations in the signal transducer and activator of transcription 3 gene are associated with sheep body weight and fatness traits

期刊: MAMMALIAN GENOME, 2021; 32 (1)

The signal transducer and activator of transcription 3 (STAT3) gene plays a crucial role in leptin-mediated energy metabolism, upon which the growth a......

Associations between SNP83 of phosphodiesterase 4D gene and carotid atherosclerosis in a southern Chinese Han population: a case-control study

期刊: MAMMALIAN GENOME, 2021; 32 (2)

Atherosclerosis was an important pathophysiological basis of atherothrombotic stroke, and phosphodiesterase 4D (PDE4D) polymorphism (SNP83/rs966221) w......

Genetic controls of Tas1r3-independent sucrose consumption in mice

期刊: MAMMALIAN GENOME, 2021; 32 (2)

We have previously used crosses between C57BL/6ByJ (B6) and 129P3/J (129) inbred strains to map a quantitative trait locus (QTL) on mouse chromosome (......

Identification and comparison of the porcine H1, U6, and 7SK RNA polymerase III promoters for short hairpin RNA expression

期刊: MAMMALIAN GENOME, 2020; 31 (3-4)

RNA polymerase III is an essential enzyme in eukaryotes for synthesis of tRNA, 5S rRNA, and other small nuclear and cytoplasmic RNAs. Thus, RNA polyme......

PKM2 ablation enhanced retinal function and survival in a preclinical model of retinitis pigmentosa

期刊: MAMMALIAN GENOME, 2020; 31 (3-4)

Retinitis pigmentosa (RP) is a neurodegenerative disorder that causes irreversible vision loss in over 1.5 million individuals world-wide. The genetic......

MALDI-TOF-MS-based high throughput genotyping of mutations associated with body measurement traits in cattle

期刊: MAMMALIAN GENOME, 2020; 31 (7-8)

Exploration of genes in relation to body measurement traits through large-scaled mutation identification is highly conductive for the genomics-assiste......

Eukaryotic translation initiation factor 3 subunit b is a novel oncogenic factor in prostate cancer

期刊: MAMMALIAN GENOME, 2020; 31 (7-8)

Prostate cancer, the second most common cancer among male adults, affects millions globally. We sought to investigate the expression and contribution ......

Intramuscular injection of tetracycline decreased gut microbial diversity in mouse

期刊: MAMMALIAN GENOME, 2020; 31 (9-12)

Antibiotics contribute a lot to human beings and can kill bacteria effectively. However, more and more studies show that antibiotics can disturb the i......

A miR-18a binding-site polymorphism in CDC42 3UTR affects CDC42 mRNA expression in placentas and is associated with litter size in pigs

期刊: MAMMALIAN GENOME, 2019; 30 (1-2)

Increasing evidence suggests that miRNA binding-site polymorphism in the 3-untranslated region (3UTR) of a target gene could affect that gene's expres......

JIF:2.34

Analysis and preliminary validation of the molecular mechanism of fat deposition in fatty and lean pigs by high-throughput sequencing

期刊: MAMMALIAN GENOME, 2019; 30 (3-4)

Fat deposition in muscle includes intramuscular fat (IMF) and intermuscular fat. IMF content is an index of pork quality; however, because IMF content......

JIF:2.34

Amplification of lncRNA PVT1 promotes ovarian cancer proliferation by binding to miR-140

期刊: MAMMALIAN GENOME, 2019; 30 (7-8)

Gene deletion or gene amplification acts as a driving factor of onset, progress, and metastasis in various cancers, including ovarian cancers. By mini......

JIF:2.34

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