期刊： TOXICOLOGY MECHANISMS AND METHODS, 2021; 31 (7)
Background Isoflurane is a commonly used inhalation anesthetic in the clinic, which can induce cognitive dysfunction and neuroinflammation. miR-212-5p......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2021; 31 (8)
Objective Epithelial mesenchymal transition (EMT) and inflammation have been identified as carcinogenic agents. This study aims to investigate whether......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2021; 31 (8)
Aristolochic acid (AA) are persistent soil pollutants in the agricultural fields of the Balkan Peninsula. Preparations containing aristolochic acid ar......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2021; 31 (6)
Aflatoxin B1 (AFB1) is a hazard food pollutant and the most toxic one of all the aflatoxins. It is mainly metabolized in the liver and exerts strong h......
期刊： TOXICOLOGY MECHANISMS AND METHODS, ; ()
Background Isoflurane inhalation can cause nerve damage, and miR-191 is abnormally expressed in nerve crush injuries. This study aimed to explore the ......
期刊： TOXICOLOGY MECHANISMS AND METHODS, ; ()
Dexmedetomidine, a potent alpha 2-adrenoceptor (alpha 2-AR) agonist, is extensively used in the operating room (OR) and intensive care unit (ICU) and ......
期刊： TOXICOLOGY MECHANISMS AND METHODS, ; ()
Macrophages can polarize into different phenotypes in response to different microenvironmental stimuli. Macrophage polarization has been assigned to t......
期刊： TOXICOLOGY MECHANISMS AND METHODS, ; ()
The transporter multidrug resistance protein 2 (MRP2) can transport some tobacco carcinogens and plays an important role in the transport of mediators......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (9)
The use of silica nanoparticles (SiNPs) is increasing in popularity; however, the emissions released during manufacturing, use and during the disposal......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (2)
How triptolide is associated with mitochondrial dysfunction and apoptosis in connection with its hepatotoxicity remains unclear. The objective of our ......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (2)
With the widespread use of pesticides, the resistance to pesticides of pests has gradually increased, caused mixed pesticides to become even more wide......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (6)
Mitogen-activated protein kinases (MAPKs) are versatile proteins that have been suggested to be involved in the regulation of lipid metabolism. This s......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (5)
Rotenone is a mitochondrial complex I inhibitor, which can cause the death of dopaminergic (DA) neurons and Parkinson's disease (PD). Currently, wheth......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (6)
Aims: Polyphyllin I, a steroidal saponin in Rhizoma paridis, which possess broad application prospects in cancer prevention and treatment. The purpose......
期刊： TOXICOLOGY MECHANISMS AND METHODS, 2020; 30 (7)
Objective: To explore the neurotoxicity and mechanism of tris(2-chloroethyl) phosphate (TCEP) exposure in mice. Methods: Total 30 adult Kunming mice w......
