期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
We have designed, synthesized, and characterized a library of 38 novel flavonoid compounds linked with amines. Some of these amine-linked flavonoids h......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6)
In vitro antifungal susceptibility profiling of 32 clinical and environmental Talaromyces marneffei isolates recovered from southern China was perform......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6)
Conventional methods utilizing in vitro protein activity assay or in vivo parasite survival to screen for malaria inhibitors suffer from high experime......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6)
A high-throughput screen of a Roche internal chemical library based on inhibition of the respiratory syncytial virus (RSV)-induced cytopathic effect (......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
Polyketide synthase 13 (Pks13) is an important enzyme found in Mycobacterium tuberculosis that condenses two fatty acyl chains to produce alpha-alkyl ......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
Two novel ISCR1-associated dfr genes, dfrA42 and dfrA43, were identified from trimethoprim (TMP)-resistant Proteus strains and were shown to confer hi......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
Recently, the incidence of drug-resistant Helicobacter pylori infection has increased. Biofilm formation confers multidrug resistance on bacteria. Mor......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
Isavuconazole (ISA) is an azole antifungal used in the treatment of invasive aspergillosis and mucormycosis. Patients with mild or moderate hepatic im......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6)
Mosquito-borne Japanese encephalitis virus (JEV) causes serious illness worldwide and is associated with high morbidity and mortality. To identify pot......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
AcrAB-TolC is a major tripartite multidrug efflux pump conferring resistance to a wide variety of compounds in Gram-negative pathogens. Many AcrB muta......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
Linezolid is an oxazolidinone antibiotic exhibiting efficacy against multi-drug-resistant (MDR) Gram-positive-related infections. However, its populat......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (5)
The growing antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious global threat to gonococcal therapy. Molecular typing is an ideal too......
期刊： ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6)
Antibiotics that can treat or prevent infectious diseases play an important role in medical therapy. However, the use of antibiotics has potentially n......
