期刊: TARGETED ONCOLOGY, 2021; 16 (4)
Background Non-small-cell lung cancer (NSCLC) accounts for most new diagnoses of lung cancer, with high morbidity and mortality worldwide. Immune chec......
期刊: TARGETED ONCOLOGY, 2021; 16 (2)
Hepatocellular carcinoma (HCC) is one of the most common cancers and a main cause of cancer-associated death worldwide. Even with the successful launc......
期刊: TARGETED ONCOLOGY, 2021; 16 (2)
Background B-Raf proto-oncogene (BRAF)-V600E mutations (BRAFmt) in colorectal cancer (CRC) predominantly occur in right-side (RS) primaries. In metast......
期刊: TARGETED ONCOLOGY, 2021; 16 (2)
Background The clinical relevance of epidermal growth factor receptor (EGFR) copy number gain in patients with EGFR mutated advanced non-small cell lu......
期刊: TARGETED ONCOLOGY, 2021; 16 (2)
Background Abemaciclib, a cyclin-dependent kinase 4 and 6 inhibitor, is approved in combination with endocrine therapy or as monotherapy for hormone r......
期刊: TARGETED ONCOLOGY, 2021; 16 (2)
Background In the global FLAURA study, first-line osimertinib, a third-generation irreversible tyrosine kinase inhibitor (TKI) of epidermal growth fac......
期刊: TARGETED ONCOLOGY, 2020; 15 (1)
Background Immunotherapy based on programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors has revolutionized the treatment......
期刊: TARGETED ONCOLOGY, 2020; 15 (2)
Background Diffuse large B-cell lymphoma (DLBCL) is a clinically heterogeneous malignancy. Following front-line immunochemotherapy, 30-40% of DLBCL pa......
期刊: TARGETED ONCOLOGY, 2020; 15 (2)
Background Previously, we demonstrated that treatment with gefitinib combined with pemetrexed plus carboplatin chemotherapy improved progression-free ......
期刊: TARGETED ONCOLOGY, 2020; 15 (3)
Background Epidermal growth factor receptor (EGFR) exon 19 deletions (19dels) appear in a large number of variants, which has not been distinguished i......
期刊: TARGETED ONCOLOGY, 2020; 15 (3)
Background Although chimeric antigen receptor (CAR) T-cell therapy targeting antigens expressed in refractory and relapsed non-Hodgkin B-cell lymphoma......
期刊: TARGETED ONCOLOGY, 2020; 15 (3)
Background Osimertinib is a standard therapy for advanced non-small cell lung cancer (NSCLC) patients with an acquired epidermal growth factor recepto......
期刊: TARGETED ONCOLOGY, 2019; 14 (6)
BackgroundDroplet digital polymerase chain reaction (ddPCR) is an emerging technology for quantitative cell-free DNA oncology applications. However, a......
期刊: TARGETED ONCOLOGY, 2019; 14 (1)
BackgroundOverexpression of epidermal growth factor receptor (EGFR) is common in pancreatic cancer and associated with the poor prognosis of this mali......
期刊: TARGETED ONCOLOGY, 2019; 14 (2)
Background Serum protein fraction (SPF) is a common parameter reflecting the nutritional and inflammatory status of the human body. However, its role ......