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A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1

期刊: CYTOTECHNOLOGY, 2022; 74 (6)

Matrine, one of the active ingredients of Sophora flavescens Ait., has a protective effect in animal models on acute liver injury and liver fibrosis. ......

JIF:1.955

Development of a novel feeding regime for large scale production of human umbilical cord mesenchymal stem/stromal cells

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

Human umbilical cord mesenchymal stem/stromal cells (hUC-MSCs) have attracted significant research interests in regenerative medicine and cell-based t......

JIF:1.955

Protective effects of liquiritin on polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis via miR-206/PI3K/AKT pathway

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

Polycystic ovarian syndrome (PCOS) is a frequent metabolic disorder in premenopausal woman, featured with increased androgen, reduced ovulation and in......

JIF:1.955

NOD2 is involved in regulating odontogenic differentiation of DPSCs suppressed by MDP through NF-kappa B/p65 signaling

期刊: CYTOTECHNOLOGY, 2022; 74 (2)

Dental pulp stem cells (DPSCs) are well known for their capable of both self-renewal and multilineage differentiation. Dental tissue diseases, include......

JIF:1.955

The roles of HOXB8 through activating Wnt/beta-catenin and STAT3 signaling pathways in the growth, migration and invasion of ovarian cancer cells

期刊: CYTOTECHNOLOGY, 2022; 74 (1)

Ovarian cancer is one of the gynecological malignancies ranked third in incidence and first in mortality in the world. Homoboxb8 (HOXB8) has been demo......

JIF:1.955

PSMB2 knockdown suppressed proteasome activity and cell proliferation, promoted apoptosis, and blocked NRF1 activation in gastric cancer cells

期刊: CYTOTECHNOLOGY, 2022; 74 (4)

Proteasome 20S Subunit Beta 2 (PSMB2) has been suggested to play several roles in cancer. However, the role of PSMB2 and its underlying mechanisms in ......

JIF:1.955

Silencing TRPM2 enhanced erastin- and RSL3-induced ferroptosis in gastric cancer cells through destabilizing HIF-1 alpha and Nrf2 proteins

期刊: CYTOTECHNOLOGY, 2022; 74 (5)

Ferroptosis is a regulated form of cell death driven by small molecules or conditions that induce lipid-based reactive oxygen species (ROS) accumulati......

JIF:1.955

Mechanical strain regulates osteoclastogenesis via modulating the PTEN/PI3K/Akt signal pathway through miR-21

期刊: CYTOTECHNOLOGY, 2022; 74 (1)

Mechanical strain regulated osteoclastic differentiation and angiogenesis are crucial for bone modeling and remodeling, and previous data indicate tha......

JIF:1.955

OCT4, SOX2 and NANOG co-regulate glycolysis and participate in somatic induced reprogramming

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

OCT4, SOX2 and NANOG (OSN) are the key factors of cell reprogramming, which are involved in the maintenance of stem cell pluripotency. Recently, it ha......

JIF:1.955

The secretome of microglia induced by IL-4 of IFN-gamma differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell by targeting the PI3K-Akt pathway

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

Microglia has been reported to be able to regulate the proliferation, differentiation and survival of adult neural stem/progenitor cells (NSPCs) by mo......

JIF:1.955

Th22/IL-22 mediates the progression of HBV-related hepatocellular carcinoma via STAT3

期刊: CYTOTECHNOLOGY, 2022; 74 (2)

T helper cell 22 are abundant in Hepatitis B Virus-related hepatocellular carcinoma tissue, and the main cytokine interleukin 22 produced by Th22 cell......

JIF:1.955

Protective effects of lidocaine on polycystic ovary syndrome through modulating ovarian granulosa cell physiology via PI3K/AKT/mTOR pathway

期刊: CYTOTECHNOLOGY, 2022; 74 (2)

Polycystic ovary syndrome (PCOS) is a common endocrine condition in women that causes adverse reproductive and metabolic effects. PCOS is a heterogene......

JIF:1.955

Static magnetic field regulates proliferation, migration, and differentiation of human dental pulp stem cells by MAPK pathway

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

Magnetic materials are now commonly used in dental clinics. These materials generally produce a static magnetic field (SMF). While it is known that SM......

JIF:1.955

Targeting RPL23 restores chemosensitivity of cisplatin-resistant ovarian carcinoma by inhibiting EMT

期刊: CYTOTECHNOLOGY, 2022; 74 (3)

Chemoresistance is the inevitable outcome of chemotherapy for epithelial ovarian carcinoma (EOC), and its mechanism is still not fully understood. Thi......

JIF:1.955

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