期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (10)
Liquid-liquid phase separation (LLPS) triages protein cargoes for autophagic degradation. In this issue, Ohshima et al. (2022. J. Cell Biol.) demonstr......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (12)
Zhu et al. review the current knowledge on how mTORC1 activity is connected to cell death regulation through metabolic and signaling pathways. The mec......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (4)
Wang et al. identify Peln1 as a key chromatin lncRNA that controls the pluripotency exit in stem cells by trans regulating the Oct4 promoter and intra......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (4)
Migrasomes are recently discovered vesicle-like structures on retraction fibers of migrating cells that have been linked with transfer of cellular con......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (7)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of the ongoing global pandemic of coronavirus disease 2019 (COVID-......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (1)
The ESCRT protein CHMP2B and the RNA-binding protein TDP-43 are both associated with ALS and FTD. The pathogenicity of CHMP2B has mainly been consider......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (5)
Very little is known about how the material properties of protein condensates assembled via liquid-liquid phase separation (LLPS) are maintained and a......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (8)
IRSp53 (aka BAIAP2) is a scaffold protein that couples membranes with the cytoskeleton in actin-filled protrusions such as filopodia and lamellipodia.......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (9)
Membrane contact site (MCS)-mediated organelle interactions play essential roles in the cell. Quantitative analysis of MCSs reveals vital clues for ce......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (1)
During sexual reproduction, the zygote must inherit exactly one centrosome (spindle pole body [SPB] in yeasts) from the gametes, which then duplicates......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (6)
Tissue-resident macrophages play essential functions in the maintenance of tissue homeostasis and repair. Recently, the endocardium has been reported ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (7)
Multivesicular bodies (MVBs) contain intralumenal vesicles that are delivered to lysosomes for degradation or released extracellularly for intercellul......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (5)
The time course of signaling by peptide hormones, neural peptides, and other neuromodulators depends on their storage inside dense core vesicles (DCVs......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (7)
Branching microtubule (MT) nucleation is mediated by the augmin complex and gamma-tubulin ring complex (gamma-TuRC). However, how these two complexes ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (1)
Primary cilia transduce diverse signals in embryonic development and adult tissues. Defective ciliogenesis results in a series of human disorders coll......
