期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Background Microglia are active modulators of Alzheimer's disease but their role in relation to amyloid plaques and synaptic changes due to rising amy......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Background Understanding the long-term effects of coronavirus disease 2019 (COVID-19) on cognitive function is essential for monitoring the cognitive ......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD) and are associated with accelerated cognitive impairment and ear......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Mass spectrometry-based proteomics empowers deep profiling of proteome and protein posttranslational modifications (PTMs) in Alzheimer's disease (AD).......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Introduction Passive immunotherapies targeting A beta continue to be evaluated as Alzheimer's disease (AD) therapeutics, but there remains debate over......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Background: Parkinson's disease (PD) is a prevalent neurological disease in the elderly with increasing morbidity and mortality. Despite enormous effo......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Background Before the deposition of amyloid-beta plaques and the onset of learning memory deficits, patients with Alzheimer's disease (AD) experience ......
期刊： MOLECULAR NEURODEGENERATION, 2021; 16 (1)
Background Oxidative stress is a common cause of neurodegeneration and plays a central role in retinal degenerative diseases. Heme oxygenase-1 (HMOX1)......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Background Loss of function of triggering receptor expressed on myeloid cell 2 (TREM2), a key receptor selectively expressed by microglia in the brain......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Background Acute glaucoma, characterized by a sudden elevation in intraocular pressure (IOP) and retinal ganglion cells (RGCs) death, is a major cause......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Background Multiple missense mutations in Leucine-rich repeat kinase 2 (LRRK2) are associated with familial forms of late onset Parkinson's disease (P......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Background Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of neuroinflam......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-dependent dementia. There is currently no effective treatment for A......
期刊： MOLECULAR NEURODEGENERATION, 2020; 15 (1)
Background Based on amyloid cascade and tau hypotheses, protein biomarkers of different A beta and tau species in cerebrospinal fluid (CSF) and blood/......
