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Studies on activation and regulation of the coagulation cascade in chronic rhinosinusitis with nasal polyps

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 150 (2)

Background: Increased activation of the coagulation cascade and diminished fibrinolysis combine to promote fibrin deposition and polyp formation in ch......

Impact of Allergic Rhinitis and Asthma on COVID-19 Infection, Hospitalization, and Mortality

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (1)

BACKGROUND: It remains unclear if patients with allergic rhinitis (AR) and/or asthma are susceptible to corona virus disease 2019 (COVID-19) infection......

The Case for Prompt Salvage Infant Peanut Oral Immunotherapy Following Failed Primary Prevention

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (10)

Recent guideline recommendations have shifted from recommending prolonged avoidance of allergenic foods in the first 3 years of life to a primary prev......

Prospective Study on the Efficacy and Impact of Cascade Screening and Evaluation of Hereditary (CaSE-HAE)

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (11)

BACKGROUND: Recommendations regarding family screening for hereditary angioedema (HAE) remain variable and mostly based on expert opinion. Studies eva......

Acute air pollution exposure increases TET enzymes in human PBMCs

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 150 (2)

Background: Exposure to traffic-related air pollution is associated with increased morbidity and mortality. Negative health impact of diesel exhaust (......

The Development of the Mucosal Concept in Chronic Rhinosinusitis and Its Clinical Implications

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (3)

In the last 2 decades, an increasing understanding of pathophysiological mechanisms in chronic rhinosinusitis (CRS) opened an avenue from phenotyping ......

Evaluation of Combination Therapy With Etanercept and Systemic Corticosteroids for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Observational Study

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (5)

BACKGROUND: Stevens-Johnson syndrome-toxic epidermal necrolysis (SJS-TEN) are fatal severe cutaneous adverse reactions, without consensus on the medic......

Comparison of Different Biologics for Treating Chronic Rhinosinusitis With Nasal Polyps: A Network Analysis

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2022; 10 (7)

BACKGROUND: Several promising clinical trials have demonstrated the effects of type 2 biologics compared with placebos in chronic rhinosinusitis with ......

Chronic Respiratory Diseases and the Outcomes of COVID-19: A Nationwide Retrospective Cohort Study of 39,420 Cases

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2021; 9 (7)

BACKGROUND: Chronic respiratory diseases (CRD) are common among patients with coronavirus disease 2019 (COVID-19). OBJECTIVES: We sought to determine ......

Characterization of Asthma Trajectories from Infancy to Young Adulthood

期刊: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2021; 9 (6)

BACKGROUND: Development of asthma is complicated by the multidimensional nature of the disease. OBJECTIVE: To identify and characterize trajectories o......

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