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Drug-drug cocrystals: Opportunities and challenges

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and c......

Innovative color jet 3D printing of levetiracetam personalized paediatric preparations

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

3D printing is a promising technology used in the fabrication of complex oral dosage delivery pharmaceuticals. This study first reports an innovative ......

Intra-Articular injection of acid-sensitive stearoxyl-ketal-dexamethasone microcrystals for long-acting arthritis therapy

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (2)

Despite advances in treatment of chronic arthritis, there is still a strong need for the development of long-acting formulations that can enable local......

In vitro - in vivo - in silico approach in the development of inhaled drug products: Nanocrystal-based formulations with budesonide as a model drug

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

This study aims to understand the absorption patterns of three different kinds of inhaled formulations via in silico modeling using budesonide (BUD) a......

Gas-blasting nanocapsules to accelerate carboplatin lysosome release and nucleus delivery for prostate cancer treatment

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (2)

To improve therapeutic effect and reduce severely side effects of carboplatin (CBP), the gas-generating nanocapsules were developed to accelerate CBP ......

The application of label-free imaging technologies in transdermal research for deeper mechanism revealing

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and th......

Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

Sorafenib, a molecular targeted multi-kinase inhibitor, has received considerable interests in recent years due to its significant profiles of efficac......

pH-sensitive micelles self-assembled from star-shaped TPGS copolymers with ortho ester linkages for enhanced MDR reversal and chemotherapy

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

TPGS approved by FDA can be used as a P-gp inhibitor to effectively reverse multi-drug resistance (MDR) and as an anticancer agent for synergistic ant......

Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

Most biopharmaceutics classification system (BCS) class IV drugs, with poor solubility and inferior permeability, are also substrates of P-glycoprotei......

A computer-aided chem-photodynamic drugs self-delivery system for synergistically enhanced cancer therapy

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (2)

The therapeutic strategy that gives consideration to the combination of photodynamic therapy and chemotherapy, has emerged as a potential development ......

Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (3)

Homodimeric prodrug-based self-assembled nanoparticles, with carrier-free structure and ultrahigh drug loading, is drawing more and more attentions. H......

Recent advances of biomimetic nano-systems in the diagnosis and treatment of tumor

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (2)

The lack of effective methods of diagnosis and treatment presents a major barrier to combat against tumor. The biomimetic concept is an emerging field......

SARS-CoV-2 vaccine research and development: Conventional vaccines and biomimetic nanotechnology strategies

期刊: ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 16 (2)

The development of a massively producible vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is essent......

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