NEJM:真菌性感染性心内膜炎1例

2019-02-10 杨中华 脑血管病及重症文献导读

76岁,男性。因为呼吸短促加重到急诊室就诊。

76岁,男性。

因为呼吸短促加重到急诊室就诊。

既往充血性心力衰竭,射血分数45%,9个月前经导管主动脉瓣置换术

体温39° C,心脏听诊可闻及5级收缩期杂音(可触及颤动)。胸片显示肺水肿。实验室白细胞1.6万/mm3(正常0.4-1.0),C 反应蛋白120mg/L(正常<5)。六次连续血培养皆为近平滑假丝酵母菌(Candida parapsilosis)。

开始给予抗真菌治疗,随后经食道超声确诊为人工瓣膜心内膜炎,可见巨大赘生物梗阻被修复的瓣膜(下图)



外科主动脉瓣置换术中可见赘生物(下图,长箭头)和正常的瓣膜(短箭头):



2个月后死于误吸。

原始出处:
Thierry Carrel and Balthasar Eberle. Candida Endocarditis after TAVR. NEJM. Jan 2019.

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    2019-02-12 zhaojie88
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    2019-02-12 执迷不悔

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