Chest:吸水烟与冠状动脉钙化的关系

2019-02-10 xing.T MedSci原创

由此可见,只吸水烟与CAC的存在和程度相关,CAC的风险增加两倍,归为高CHD风险类别的风险是其他危险因素的三倍。

吸水烟越来越受欢迎,部分原因在于与吸烟相比减少了伤害。近日,呼吸领域权威杂志chest上发表了一篇研究文章,该研究在社区样本中评估了水烟与冠状动脉钙化(CAC)(冠心病(CHD)风险的标志)之间的关系。

研究人员从黎巴嫩和卡塔尔的社区招募了175名只吸水烟者和170名35岁以上的非吸烟者,使用经过验证的问卷评估吸水烟情况,并使用多维计算机断层扫描评估CAC评分。研究人员使用针对CHD危险因素调整的回归分析评估吸水烟与有无CAC和程度之间的关联。

41%的吸水烟者存在CAC,而28%非吸烟者存在CAC,p=0.01,在吸水烟者中平均CAC为90.6 Agatston单位(AU)(SD=400.3),在非吸烟者中平均CAC为52.4 AU(SD=218.6)。在调整后的分析中,吸水烟者患CAC的调整几率明显较高(OR=2.20,95%CI[1.20-4.01],p=0.01);并且CAC>300AU(OR=3.41,95%CI[1.08-10.77],p=0.04)或相比于非吸烟者CAC>75%年龄、性别和种族预测值(OR=3.11,95%CI[1.55-6.24],p=0.001)定义为高CHD风险类别。CAC程度与吸烟持续时间(β=0.17/年,95%CI[0.05-0.29],p=0.004)或吸烟持续时间与每日吸水烟数(β)的乘积显著相关(β=0.04/水烟每年,95%CI[0.003-0.07],p=0.03)。

由此可见,只吸水烟与CAC的存在和程度相关,CAC的风险增加两倍,归为高CHD风险类别的风险是其他危险因素的三倍。

原始出处:

Hassan A. Chami,et al.The Association of Waterpipe Smoking and Coronary Artery Calcium in a Community-Based Sample.chest.2019.https://journal.chestnet.org/article/S0012-3692(19)30028-5/fulltext

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    2019-04-22 仁医06
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    2019-02-12 仁医06