Hypertension:美国1970年至2010年孕妇慢性高血压患病率的变化趋势

2019-09-11 medsci MedSci原创

近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员估计了孕妇慢性高血压患病率的变化,并评估了肥胖和吸烟变化与这些趋势相关的程度。 研究人员设计了一项基于人群的横断面研究,分析了1970年至2010年美国超过1.51亿名存在分娩相关住院的妇女。产妇年龄、分娩年份(时期)和产妇出生年份(分娩队列),以及种族,被视为慢性高血压的危险因素。通过年龄-时期-队列模型得出与年

近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员估计了孕妇慢性高血压患病率的变化,并评估了肥胖和吸烟变化与这些趋势相关的程度。

研究人员设计了一项基于人群的横断面研究,分析了1970年至2010年美国超过1.51亿名存在分娩相关住院的妇女。产妇年龄、分娩年份(时期)和产妇出生年份(分娩队列),以及种族,被视为慢性高血压的危险因素。通过年龄-时期-队列模型得出与年龄、时期和出生队列相关的慢性高血压的患病率、比率以及95%CI。研究人员还探究了肥胖和吸烟率的变化如何影响年龄-时期-队列效应。

慢性高血压的总体患病率为0.63%,黑人女性(1.24%)的发病率比白人女性高出2倍(0.53%;比率为2.31; 95%CI为2.30-2.32)。在年龄-时期-队列分析中,慢性高血压的发病率随着年龄的增长而急剧增加,从1970年的0.11%上升到2010年的1.52%(比率为13.41; 95%CI为13.22-13.61)。高血压发病率平均每年增加6%(95%CI为5-6),白人女性(7%; 95%CI为6%-7%)的增幅略高于黑人女性(4%; 95%CI为3%-4%)。对肥胖和吸烟率变化进行调整后,其与年龄和时期效应无关。

研究人员观察到慢性高血压患病率随着年龄和年份的增长而显著增加,慢性高血压患者的种族差异超过2倍。 

原始出处:

Cande V. Ananth.et al.Changes in the Prevalence of Chronic Hypertension in Pregnancy, United States, 1970 to 2010.Hypertension.2019.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.12968

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    2019-09-12 天地飞扬

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由此可见,该研究的结果表明孕妇暴露于PM2.5及其成分与孕妇fT4水平之间呈负相关。孕妇fT4可能作为暴露于PM2.5及其成分和出生体重之间相关性的介导因素。

NEJM:胎盘植入累及孕妇膀胱-病例报道

胎盘植入的特征是胎盘绒毛膜绒毛侵入子宫肌层和超出子宫肌层,有时进入周围结构。贴壁胎盘在分娩时无法分离,可能导致灾难性出血和严重的母体并发症。