J Allergy Clin Immunol Pract:欧洲鸡蛋过敏风险因子群体研究

2020-01-04 AlexYang MedSci原创

鸡蛋是引起食物过敏的一种最常见的诱因之一,但是其风险因素的数据很少。最近,有研究人员评估了欧洲群体中鸡蛋过敏的风险因素,尤其是湿疹。研究总共包括了12049名婴幼儿,其中9336名(77.5%)跟踪调查持续了2年。其中共有86名婴幼儿鸡蛋过敏(84名有DBPCFC鉴定),并与140名对照匹配。研究发现,与鸡蛋过敏相关的独立因子包括了过去/现在患有湿疹(aOR, 9.21; 95% CI, 2.65

鸡蛋是引起食物过敏的一种最常见的诱因之一,但是其风险因素的数据很少。最近,有研究人员评估了欧洲群体中鸡蛋过敏的风险因素,尤其是湿疹。

研究总共包括了12049名婴幼儿,其中9336名(77.5%)跟踪调查持续了2年。其中共有86名婴幼儿鸡蛋过敏(84名有DBPCFC鉴定),并与140名对照匹配。研究发现,与鸡蛋过敏相关的独立因子包括了过去/现在患有湿疹(aOR, 9.21; 95% CI, 2.65-32.04)、特发性皮炎评分(1.54/5 units; 1.28-1.86)、出生第1周内抗生素使用(6.17; 1.42-26.89)和现在患有鼻炎(3.02; 1.04-8.78)。湿疹严重度的增加与鸡蛋过敏可能性的增加相关。另外,湿疹被报道在鸡蛋过敏的前3.6个月(SE,0.5)开始。开始食用鸡蛋的年龄与鸡蛋过敏不存在相关性。

最后,研究人员指出,与花生过敏相似,湿疹与鸡蛋过敏的发展相关,并且相关性随着湿疹严重度的增加而增强。食用鸡蛋的年龄与鸡蛋过敏无关。早期使用抗生素是否是鸡蛋过敏的风险因子仍旧需要进一步调查。

原始出处:

Grimshaw KEC, Roberts G, Selby A et al. Risk Factors for Hen's Egg Allergy in Europe: EuroPrevall Birth Cohort. J Allergy Clin Immunol Pract. 14 Dec 2019.

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    2020-03-22 xjy13
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1717020, encodeId=a88b1e1702049, content=<a href='/topic/show?id=f8a98002eb1' target=_blank style='color:#2F92EE;'>#群体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80027, encryptionId=f8a98002eb1, topicName=群体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6c0832353243, createdName=xjy13, createdTime=Sun Mar 22 09:08:00 CST 2020, time=2020-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1813879, encodeId=3ebd18138e921, content=<a href='/topic/show?id=ccc2940e2fe' target=_blank style='color:#2F92EE;'>#过敏风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94072, encryptionId=ccc2940e2fe, topicName=过敏风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=68b666, createdName=zhangying8788, createdTime=Sat Mar 21 00:08:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967034, encodeId=9f52196e034ea, content=<a href='/topic/show?id=b31a800321e' target=_blank style='color:#2F92EE;'>#群体研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80032, encryptionId=b31a800321e, topicName=群体研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e1cc90, createdName=rebeccajiejie, createdTime=Sun Nov 22 04:08:00 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755036, encodeId=01741e5503667, content=<a href='/topic/show?id=fa3410296566' target=_blank style='color:#2F92EE;'>#鸡蛋过敏#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102965, encryptionId=fa3410296566, topicName=鸡蛋过敏)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7d2536824918, createdName=马龙, createdTime=Mon Nov 02 14:08:00 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329323, encodeId=8176132932362, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon Jan 06 05:08:00 CST 2020, time=2020-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339260, encodeId=7e171339260f5, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Mon Jan 06 05:08:00 CST 2020, time=2020-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529276, encodeId=de3515292e615, content=<a href='/topic/show?id=6eb91008e03b' target=_blank style='color:#2F92EE;'>#风险因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100870, encryptionId=6eb91008e03b, topicName=风险因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c2d411920658, createdName=cenghis, createdTime=Mon Jan 06 05:08:00 CST 2020, time=2020-01-06, status=1, ipAttribution=)]
    2020-01-06 膀胱癌
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