Crit Care:NLR比对COVID-19患者疾病严重程度和死亡的预测价值

2020-11-16 MedSci原创 MedSci原创

NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值。评估NLR可以帮助临床医生及早发现潜在的严重病例,进行早期分诊并及时开始有效的治疗,这可以降低COVID-19患者的整体死亡率。

2019冠状病毒病(COVID-19)是一种高度传染性疾病,已在世界范围内迅速传播,仍然对全球公共健康构成巨大威胁。严重或危重病例预后较差,因此,及早发现潜在的严重或危重病例并及时为目标患者提供治疗至关重要。在治疗COVID-19患者的临床实践中,研究人员观察到严重患者的中性粒细胞与淋巴细胞之比(NLR)高于轻度患者。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,研究人员进行了一项系统评价和荟萃分析,以评估NLR对COVID-19患者疾病严重程度和死亡的预测价值。

研究人员检索了PubMed、EMBASE、中国知网(CNKI)和万方数据库,以确定符合条件的研究(截至2020年8月11日)。两位作者独立筛选研究并提取数据。通过诊断准确性研究质量评估2(QUADAS-2)评估了纳入研究的方法学质量。

该分析共涉及1579名患者和13项研究,这些研究报告了NLR对疾病严重程度的预测价值。合并灵敏度(SEN)、特异性(SPE)和曲线下面积(AUC)分别为0.78(95%CI为0.70-0.84)、0.78(95%CI为0.73-0.83)和0.85(95%CI为0.81-0.88) 。共计2967名患者的10项研究报告了NLR对死亡的预测价值。合并的SEN、SPE和AUC分别为0.83(95%CI为0.75-0.89)、0.83(95%CI为0.74-0.89)和0.90(95%CI为0.87-0.92)。

由此可见,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值。评估NLR可以帮助临床医生及早发现潜在的严重病例,进行早期分诊并及时开始有效的治疗,这可以降低COVID-19患者的整体死亡率。

这个结论与目前一些模型是相似的,这是一些可以在线使用的模型:

新冠肺炎住院患者死亡风险评估(4C致死率评分)

新冠肺炎患者疾病恶化风险评估(COMPASS-COVID-19评分)

新冠肺炎患者免疫超敏反应预测评分(CHIR评分)

新冠肺炎(COVID-19)住院后重症风险预测工具(COVID-GRAM)

原始出处:

Xiaoming Li.et al.Predictive values of neutrophil-to-lymphocyte ratio on disease severity and mortality in COVID-19 patients: a systematic review and meta-analysis.Critical Care.2020.https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03374-8

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    2020-11-22 ms7000000464442608

    感谢

    0

  2. 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    2020-11-20 药师小王

    形势严峻啊

    0

  3. 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createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=901091, encodeId=69c0901091c1, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3a25435622, createdName=ms7000000464442608, createdTime=Sun Nov 22 07:04:33 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900832, encodeId=a60a9008327a, content=形势严峻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5c0c541ffceb4f11b0948c3e262b6e70/5b6894da824e43cca0ba37dddeca4910.jpg, createdBy=f45a2515633, createdName=药师小王, createdTime=Fri Nov 20 16:28:20 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1297492, encodeId=1b2c129e49294, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407762, encodeId=2880140e76244, content=<a href='/topic/show?id=a22412862b3' target=_blank style='color:#2F92EE;'>#NLR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12862, encryptionId=a22412862b3, topicName=NLR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cd32710930, createdName=yuandd, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
    2020-11-18 yuandd
  5. [GetPortalCommentsPageByObjectIdResponse(id=901091, encodeId=69c0901091c1, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3a25435622, createdName=ms7000000464442608, createdTime=Sun Nov 22 07:04:33 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900832, encodeId=a60a9008327a, content=形势严峻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5c0c541ffceb4f11b0948c3e262b6e70/5b6894da824e43cca0ba37dddeca4910.jpg, createdBy=f45a2515633, createdName=药师小王, createdTime=Fri Nov 20 16:28:20 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1297492, encodeId=1b2c129e49294, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407762, encodeId=2880140e76244, content=<a href='/topic/show?id=a22412862b3' target=_blank style='color:#2F92EE;'>#NLR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12862, encryptionId=a22412862b3, topicName=NLR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cd32710930, createdName=yuandd, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=901091, encodeId=69c0901091c1, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3a25435622, createdName=ms7000000464442608, createdTime=Sun Nov 22 07:04:33 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900832, encodeId=a60a9008327a, content=形势严峻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5c0c541ffceb4f11b0948c3e262b6e70/5b6894da824e43cca0ba37dddeca4910.jpg, createdBy=f45a2515633, createdName=药师小王, createdTime=Fri Nov 20 16:28:20 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1297492, encodeId=1b2c129e49294, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407762, encodeId=2880140e76244, content=<a href='/topic/show?id=a22412862b3' target=_blank style='color:#2F92EE;'>#NLR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12862, encryptionId=a22412862b3, topicName=NLR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cd32710930, createdName=yuandd, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
    2020-11-17 lovetcm

    #新冠肺炎##Covid-19#,NLR小指标大用途!与很多评分模型的结论是一致的。

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=901091, encodeId=69c0901091c1, content=感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a3a25435622, createdName=ms7000000464442608, createdTime=Sun Nov 22 07:04:33 CST 2020, time=2020-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=900832, encodeId=a60a9008327a, content=形势严峻啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5c0c541ffceb4f11b0948c3e262b6e70/5b6894da824e43cca0ba37dddeca4910.jpg, createdBy=f45a2515633, createdName=药师小王, createdTime=Fri Nov 20 16:28:20 CST 2020, time=2020-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1297492, encodeId=1b2c129e49294, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407762, encodeId=2880140e76244, content=<a href='/topic/show?id=a22412862b3' target=_blank style='color:#2F92EE;'>#NLR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12862, encryptionId=a22412862b3, topicName=NLR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cd32710930, createdName=yuandd, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
    2020-11-17 ms6000000637882032

    有价值,很实用

    0

  8. 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encodeId=1b2c129e49294, content=<a href='/topic/show?id=c0385134ab' target=_blank style='color:#2F92EE;'>#COVID-19患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5134, encryptionId=c0385134ab, topicName=COVID-19患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6976269, createdName=zhangph, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407762, encodeId=2880140e76244, content=<a href='/topic/show?id=a22412862b3' target=_blank style='color:#2F92EE;'>#NLR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12862, encryptionId=a22412862b3, topicName=NLR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8cd32710930, createdName=yuandd, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
    2020-11-17 18922102935

    新冠已成常态防护

    0

  9. 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14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎), TopicDto(id=5132, encryptionId=f52851329b, topicName=Covid-19)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Nov 17 11:42:58 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899818, encodeId=5e2f89981832, content=有价值,很实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f68b5425700, createdName=ms6000000637882032, createdTime=Tue Nov 17 11:19:13 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899801, encodeId=4be689980151, content=新冠已成常态防护, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201117/a466d618d3054054a5f41e9bff152621/86d4c8ee4282463a898cf7cab8f03489.jpg, createdBy=97805435473, createdName=18922102935, createdTime=Tue Nov 17 10:25:20 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899782, encodeId=bd7c899e8299, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a>,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58078, encryptionId=46ce580e865, topicName=新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Tue Nov 17 09:25:10 CST 2020, time=2020-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899756, encodeId=abbd899e5634, content=早日战胜新冠, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200910/7e96bbab0c5c420e8fe7846dcdd38c29/2b6be8f4b6284022a808d4f619b7aed6.jpg, createdBy=2aaa1602125, createdName=opzoro, createdTime=Tue Nov 17 06:56:12 CST 2020, time=2020-11-17, status=1, ipAttribution=)]
    2020-11-17 神盾医疗局局长Jack

    #新冠肺炎#,NLR对COVID-19患者的疾病严重程度和死亡具有良好的预测价值

    0

  10. 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14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626507, encodeId=196a162650ecd, content=<a href='/topic/show?id=558b100221c7' target=_blank style='color:#2F92EE;'>#预测价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100221, encryptionId=558b100221c7, topicName=预测价值)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e5f621038683, createdName=changjitao2016, createdTime=Wed Nov 18 14:53:06 CST 2020, time=2020-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=899833, encodeId=e2db899833d4, content=<a href='/topic/show?id=46ce580e865' target=_blank style='color:#2F92EE;'>#新冠肺炎#</a><a href='/topic/show?id=f52851329b' target=_blank style='color:#2F92EE;'>#Covid-19#</a>,NLR小指标大用途!与很多评分模型的结论是一致的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, 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    2020-11-17 opzoro

    早日战胜新冠

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