JAHA:周围动脉疾病患者急性失代偿性心衰再入院分析

2020-10-26 MedSci原创 MedSci原创

伴有PAD的ADHF患者有更高的ADHF再入院率。在该高危人群中应采取预防ADHF再入院的措施。

周围动脉疾病(PAD)既是常见的合并症,也是导致心力衰竭的因素。心力衰竭患者PAD是否与失代偿心衰再入院有关尚未明确。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,自2005年以来,社区动脉粥样硬化风险(ARIC)研究已经对住院的急性失代偿性心衰(ADHF)进行了积极的监测,并且事件得到了医生的审查证实。

从2005年到2016年,1481例ADHF患者住院治疗并且活着出院(平均年龄为78岁;白人占69%)。其中,207名(14%)患有PAD。患有PAD的受试者中,男性(55% vs. 44%)和吸烟者(17% vs. 8%)更多,冠心病的患病率更高(72% vs. 52%)。PAD患者在出院后30天(11% vs. 7%)和1年内(39% vs. 28%)至少一次ADHF再入院风险增加。调整后,PAD与30天内ADHF再次入院的风险增加2倍相关(HR为2.02;95%CI为1.14-3.60),1年内ADHF再次入院的风险升高60%(HR为1.60; 95%CI为1.25-2.05)。射血分数降低的心衰患者(HR为2.01;95%CI为1.29-3.13)相比于射血分数降低的心衰患者(HR为1.04;95%CI为0.69-1.56),PAD与1年内ADHF再入院风险的关联更强;相互作用P=0.05。

由此可见,伴有PAD的ADHF患者有更高的ADHF再入院率。在该高危人群中应采取预防ADHF再入院的措施。

原始出处:

Zainali Chunawala.et al.Recurrent Admissions for Acute Decompensated Heart Failure Among Patients With and Without Peripheral Artery Disease: The ARIC Study.J AM HEART ASSOC.2020.https://www.ahajournals.org/doi/full/10.1161/JAHA.120.017174

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    2020-11-06 ms4000000194031466

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    2020-10-29 Lexi

    伴有PAD的ADHF患者有更高的ADHF再入院率。在该高危人群中应采取预防ADHF再入院的措施。

    0

  5. 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    2020-10-28 zhaohui6731
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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201026/384b4f679da4456d9509d77954ef7e21/73f4281675204be69112bc911522d1a9.jpg, createdBy=336e5429283, createdName=ms3000000546125468, createdTime=Mon Oct 26 23:03:32 CST 2020, time=2020-10-26, status=1, ipAttribution=)]
    2020-10-27 周泡泡
  8. 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    2020-10-27 ms7000001878665027

    点赞

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201026/384b4f679da4456d9509d77954ef7e21/73f4281675204be69112bc911522d1a9.jpg, createdBy=336e5429283, createdName=ms3000000546125468, createdTime=Mon Oct 26 23:03:32 CST 2020, time=2020-10-26, status=1, ipAttribution=)]
    2020-10-27 Lexi

    伴有PAD的ADHF患者有更高的ADHF再入院率。在该高危人群中应采取预防ADHF再入院的措施。

    0

  10. 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    2020-10-26 ms3000000546125468

    学习了

    0

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