JAHA:青少年肥胖对成年心血管代谢风险的影响

2020-07-06 MedSci原创 MedSci原创

年轻时期超重或者肥胖对未来健康的长期影响尚不清楚。本研究目的是评估从青年时期超重或肥胖的持续时间是否与成人心脏代谢风险相关。

年轻时期超重或者肥胖对未来健康的长期影响尚不清楚。本研究目的是评估从青年时期超重或肥胖的持续时间是否与成人心脏代谢风险相关。

本研究纳入分析了1268名3-18岁的青少年,成年的不良结局包括2型糖尿病、空腹血糖受损、高胰岛素水平、颈动脉内膜中层厚度高、高血压、低高密度脂蛋白胆固醇、高低密度脂蛋白胆固醇和甘油三酯、动脉脉搏波速度、颈动脉顺应性、弹性模量高,和刚度指数。基线时的超重/肥胖比率为7.9%,31年随访后的比率为55.9%。调整混杂因素后,超重或肥胖持续时间较长与所有不良结果的风险增加均相关。当体重指数进一步调整时,这些相关性消失或显着减少。

研究结果显示,相比于儿童期超重或肥胖,成人期超重或肥胖对成人心脏代谢健康更为重要。

原始出处:

Feitong W et al.Association of Body Mass Index in Youth With Adult Cardiometabolic Risk.JAHA.2020 July.

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    2020-07-08 zhaohui6731
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