Sci Rep:注意力缺陷多动症与过敏症状和低水平的血红蛋白和血清素相关

2018-07-24 AlexYang MedSci原创

最近,有研究人员调查了是否常见的并发症或者生化因子,比如过敏性疾病、贫血、炎症和神经传导物质,单独或者组合地与注意力缺陷多动症障碍(ADHD)风险的增加相关。研究募集了216名诊断为ADHD的儿童,包括了216名在年龄、性别、身高、体重和年纪匹配的对照,他们均来自台北市的小学。研究人员利用哮喘和过敏国际调查问卷的儿童调查问卷测量了过敏症状,搜集了空腹静脉血来分析全血细胞计数、白细胞分类计数、免疫球

最近,有研究人员调查了是否常见的并发症或者生化因子,比如过敏性疾病、贫血、炎症和神经传导物质,单独或者组合地与注意力缺陷多动症障碍(ADHD)风险的增加相关。

研究募集了216名诊断为ADHD的儿童,包括了216名在年龄、性别、身高、体重和年纪匹配的对照,他们均来自台北市的小学。研究人员利用哮喘和过敏国际调查问卷的儿童调查问卷测量了过敏症状,搜集了空腹静脉血来分析全血细胞计数、白细胞分类计数、免疫球蛋白(lg)E水平和血清素水平(5-HT)。研究发现,鼻炎(OR=2.08, 95% CI=1.42-3.05)和湿疹(OR=1.72, 95% CI=1.02-2.88)症状与ADHD风险的增加显著相关。与对照儿童相比,患有ADHD的儿童表现出了明显更低的血红蛋白(p=0.001)和5-HT(p<0.001),以及更高的lgE水平(p<0.001)和嗜酸粒细胞数(P=0.001)。另外,ADHD风险上述生化危险因素存在的存在而增加(1个因素: OR=1.87, 95% CI=0.87-4.18;2个因素: OR=2.90, 95% CI=1.29-6.48;3个因素: OR=4.47, 95% CI=1.97-10.13;4个因素: OR=6.53, 95% CI=2.43-17.57)。

最后,研究人员指出,他们的发现表明了ADHD的病因是多方面的,并且上述的因素也是ADHD的病因一部分。

原始出处:


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    2018-07-26 lq1767
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    2018-07-24 1e0f8808m18(暂无匿称)

    学习了,谢谢分享。

    0

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