JACC:ST段抬高型心肌梗死患者急性心衰的发生和预后存在性别差异

2019-11-06 不详 MedSci原创

ST段抬高型心肌梗死(STEMI)合并急性心衰症状与死亡率增高有关。然而心衰的发展和预后是否存在性别差异尚不清楚。本研究的目的旨在评估STEMI患者性别、急性心衰和预后的相关性。本研究纳入分析了ISACS-TC数据库中的患者,主要终点事件是住院期间心衰Killip分级≥II和30天死亡风险。最终共纳入了10443名患者(女性占3112名),经多变量分析调整后发现,女性患者的新发急性心衰发生率明显高

ST段抬高型心肌梗死(STEMI)合并急性心衰症状与死亡率增高有关。然而心衰的发展和预后是否存在性别差异尚不清楚。本研究的目的旨在评估STEMI患者性别、急性心衰和预后的相关性。

本研究纳入分析了ISACS-TC数据库中的患者,主要终点事件是住院期间心衰Killip分级≥II和30天死亡风险。最终共纳入了10443名患者(女性占3112名),经多变量分析调整后发现,女性患者的新发急性心衰发生率明显高于男性(25.1% vs. 20.0%, [OR]: 1.34; 95% [CI]: 1.21 - 1.48),患有心衰的女性患者30天死亡风险明显高于男性(25.1% vs. 20.6%; OR: 1.29; 95% CI: 1.05 -1.58)。

研究结果显示,相比于男性,女性STEMI患者更容易出现急性心衰,伴有急性心衰的女性预后要更差。


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    2020-08-22 hbwxf
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    2019-11-08 gdsun
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    2019-11-08 hyf035
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    2019-11-06 天地飞扬

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